ArticleFrontiers in cardiovascular medicine2022
Sex difference and outcome trends following transcatheter aortic valve replacement.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Review
- Sex-Specific and Time-Dependent Outcomes After TAVR Versus SAVR: A Meta-Analysis of Randomized Trials.JACC. Advances · 2026Article
- Sex differences in echocardiographic left ventricular remodeling and clinical outcomes following transcatheter aortic valve implantation.Journal of echocardiography · 2026Article
- Early outcomes and resource utilization across contemporary transcatheter and surgical valve interventions: a single-center observational study.BMC research notes · 2026Observational
- Sex-Related Differences After Transcatheter Aortic Valve Implantation: A Retrospective Propensity-Matched Cohort.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Transcatheter Versus Surgical Aortic Valve Replacement in Women of Childbearing Age in the United States.Structural heart : the journal of the Heart Team · 2025Article
- Inpatient Outcomes of Tricuspid Transcatheter Edge-to-Edge Repair in the United States Based on Sex.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database.Journal of the American Heart Association · 2025Article
- Sex-related disparities in aortic stenosis from disease awareness to treatment: a state-of-the-art review.Journal of thoracic disease · 2024Review
- Economic Disparities in Utilization and Outcomes of Structural Heart Disease Interventions in the United States.JACC. Advances · 2024Article
- Unequal Treatment and Yentl Syndrome: Are We Providing Appropriate Care for Our TAVR Patients?JACC. Asia · 2024Article
- In-hospital safety outcomes of left atrial appendage occlusion in octogenarians and nonagenarians.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Gender-Dependent Association of Pulmonary Hypertension with Adverse Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement.International journal of general medicine · 2024Article
- Transcatheter Aortic Valve Implantation: Addressing the Subsequent Risk of Permanent Pacemaker Implantation.Journal of cardiovascular development and disease · 2023Review
- Impact of cardiac rehabilitation on pre- and post-operative transcatheter aortic valve replacement prognoses.Frontiers in cardiovascular medicine · 2023Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Based on worldwide registries, approximately 50% of patients who underwent transcatheter aortic valve replacement (TAVR) are female patients. Although TAVR procedures have improved tremendously in recent years, differences in outcome including mortality between sexes remain. We aimed to investigate the trends in TAVR in the early and new eras of utilization and to assess TAVR outcomes in female patients vs. male patients. Methods: Using the 2011-2017 National Inpatient Sample (NIS) database, we identified hospitalizations for patients with the diagnosis of aortic stenosis during which a TAVR was performed. Patients' sociodemographic and clinical characteristics, procedure complications, and mortality were analyzed. Piecewise regression analyses were performed to assess temporal trends in TAVR utilization in female patients and in male patients. Multivariable analysis was performed to identify predictors of in-hospital mortality. Results: A total of 150,647 hospitalizations for TAVR across the United States were analyzed during 2011-2017. During the study period, a steady upward trend was observed for TAVR procedures in both sexes. From 2011 to 2017, there were significantly more TAVR procedures performed in men [80,477 (53.4%)] than in women [70,170 (46.6%)]. Male patients had significantly higher Deyo-CCI score and comorbidities. Differences in mortality rates among sexes were observed, presenting with higher in-hospital mortality in women than in men, OR 1.26 [95% CI 1.18-1.35], Conclusion: Utilization of TAVR demonstrated a steady upward trend during 2011-2017, and a similar trend was presented for both sexes. Higher in-hospital mortality was recorded in female patients compared to male patients. Complication rates decreased over the years but without effect on mortality differences between the sex groups.
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