ArticleGastroenterology research and practice2022
Serum Lactate Dehydrogenase Is a Sensitive Predictor of Systemic Complications of Acute Pancreatitis.
Article in Gastroenterology research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and prognostic role of pleural effusion in patients with acute pancreatitis: a meta-analysis.Annals of medicine · 2023Pooled it
- Prognostic value of endothelial activation and stress index (EASIX) on short-term and long-term outcomes in type B aortic dissection after thoracic endovascular repair: An observational study.JTCVS structural and endovascular · 2026Article
- Endothelial stress as reflected by EASIX predicts cardiovascular morbidity and mortality: Insights from a nationally representative cohort.American heart journal plus : cardiology research and practice · 2026Article
- Association between lactate dehydrogenase to serum albumin ratio and all-cause mortality among critically ill pediatrics: a retrospective cohort study.BMC pediatrics · 2026Article
- Dynamic Assessment of Modified EASIX (m-EASIX) at 48 Hours Predicts Adverse Outcomes in Acute Pancreatitis: A Propensity Score-Matched Study.Medicina (Kaunas, Lithuania) · 2026Article
- Prognostic Significance of Lactate Dehydrogenase-to-Albumin Ratio and Neutrophil Percentage-to-Albumin Ratio in IgA Nephropathy.Biomedicines · 2026Article
- Associations of probiotics combined with Tongli Gongxia Chinese medicine with intestinal barrier biomarkers and day 7 short-chain fatty acids in patients with severe acute pancreatitis.Frontiers in cellular and infection microbiology · 2026Article
- Lactate Dehydrogenase, Interleukin-6, and 24 h Intra-Abdominal Pressure Exhibit Early Predictive Value in Hypertriglyceridemic Pancreatitis Complicated by Acute Respiratory Distress Syndrome.Emergency medicine international · 2026Article
- Development and validation of a MODS risk prediction model for organophosphorus poisoning patients.Frontiers in medicine · 2026Article
- Lactate and H3K18 Lactylation Contribute To the Exacerbation of Acute Pancreatitis by Modulating NCOA4-mediated Ferroptosis.Inflammation · 2025Article
- Apolipoprotein A-I: a non-negligible marker in hypertriglyceridemia-induced acute pancreatitis.European journal of medical research · 2025Article
- Article
- Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database.European journal of medical research · 2025Article
- Serum Lactate Dehydrogenase Levels: The Grim Reaper Sign in Acute Pancreatitis?Journal of community hospital internal medicine perspectives · 2025Article
- Lactate Dehydrogenase-to-Albumin Ratio as a Predictor of In-Hospital Mortality in Predicted Severe Acute Pancreatitis: Evidence from an 18-Year Cohort Study.Journal of inflammation research · 2025Article
- The elevated lactate dehydrogenase to albumin ratio is a risk factor for developing sepsis-associated acute kidney injury: a single-center retrospective study.BMC nephrology · 2024Article
- Ferritin and Ferritin-to-Hemoglobin Ratio as Promising Prognostic Biomarkers of Severity in Acute Pancreatitis-A Cohort Study.Biomedicines · 2024Article
- The endothelial activation and stress index is a potential prognostic indicator for patients with acute pancreatitis managed in the intensive care unit: a retrospective study.Frontiers in medicine · 2024Article
- Article
- Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute pancreatitis (AP) is a common and potentially life-threatening inflammatory disease that can cause various complications, including systemic inflammatory response syndrome (SIRS), pleural effusion, ascitic fluid, myocardial infarction, and acute kidney injury (AKI). However, there is still a lack of rapid and effective indicators to assess the disease. The aim of this study was to investigate the associations of high serum lactate dehydrogenase (LDH) levels with AP severity and systemic complications. Methods: AP patients treated from July 2014 to December 2020 were retrospectively enrolled. They were divided into elevated ( Results: There were significant differences in AP severity scores (Ranson, MODS, BISAP, APACHE II, and CTSI), hospital duration, hospital expenses, and the incidences of complications (SIRS, pleural effusion, ascitic fluid, myocardial infarction, and AKI) between the elevated and normal LDH groups. After adjusting for confounders, elevated LDH was associated with AP severity scores and hospital duration and expenses (based on linear regression analyses) and was a risk factor for the occurrence of AP complications and interventions, that is, diuretic and vasoactive agent use (based on binary logistic regression analyses). Conclusions: Elevated LDH is associated with high AP severity scores and high incidences of complications (SIRS, pleural effusion, ascitic fluid, myocardial infarction, and AKI).
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Registered trials
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