Evidence map›Paper›PMID 36329692›Full record

ArticleCase reports in ophthalmological medicine2022

Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy.

Michael J Schatz, Oscar Otero-Marquez, Richard B Rosen, Deep Parikh

Abstract readCase Reports
In one paragraph

Article in Case reports in ophthalmological medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael J SchatzThe New York Eye and Ear Infirmary, 310 East 14th Street, New York 10003, USA.ORCID https://orcid.org/0000-0002-6181-525X
Oscar Otero-MarquezThe New York Eye and Ear Infirmary, 310 East 14th Street, New York 10003, USA.ORCID https://orcid.org/0000-0003-1591-9952
Richard B RosenThe New York Eye and Ear Infirmary, 310 East 14th Street, New York 10003, USA.ORCID https://orcid.org/0000-0001-9643-3510
Deep ParikhThe New York Eye and Ear Infirmary, 310 East 14th Street, New York 10003, USA.ORCID https://orcid.org/0000-0001-5638-4144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though rare, acute macular neuroretinopathy is a well-described clinical entity. We report for the first time a detailed analysis of macular hyalocyte count and morphology during the acute phase of acute macular neuroretinopathy. We present a case of a 19-year-old man with bilateral acute onset paracentral scotomas in the setting of an antecedent viral infection. Multimodal imaging demonstrated classic features of acute macular neuroretinopathy. Further analysis revealed increased macular hyalocyte count and an activated hyalocyte morphology during the acute phase of the disease course. Multimodal imaging not only allows for greater confidence in a diagnosis and prognosis but also helps to shed light on underlying pathophysiology. The new clinical capability of monitoring cellular behavior, such as hyalocyte count and morphology, in physiological and pathological conditions may prove useful as biomarkers of early disease activity or response to therapy.

Identifiers

PMID36329692
PMCPMC9626219

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