Evidence map›Paper›PMID 36329515›Full record

ArticleJournal of nanobiotechnology2022

Photoacoustic mediated multifunctional tumor antigen trapping nanoparticles inhibit the recurrence and metastasis of ovarian cancer by enhancing tumor immunogenicity.

Xiaowen Zhong, Chenyang Li, Guangzong Zhao, Mengmeng Li, Shuning Chen, Yang Cao, Qi Wang, Jiangchuan Sun, Shenyin Zhu, Shufang Chang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xiaowen ZhongDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Chenyang LiDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Guangzong ZhaoDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Mengmeng LiDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Shuning ChenDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Yang CaoChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Qi WangState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jiangchuan SunDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Shenyin ZhuDepartment of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, People's Republic of China. zhushenyin@cqmu.edu.cn.
Shufang ChangDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China. 300502@cqmu.edu.cn.
Chongqing Medical University · CNDalian Medical University · CNSecond Affiliated Hospital of Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

Natural Science Foundation of China 81972439postgraduate research and innovation projects of Chong Municipal Education Commission CYB21180
6 · The paper itself

Abstract

The hypoimmunogenicity of tumors is one of the main bottlenecks of cancer immunotherapy. Enhancing tumor immunogenicity can improve the efficacy of tumor immunotherapy by increasing antigen exposure and presentation, and establishing an inflammatory microenvironment. Here, a multifunctional antigen trapping nanoparticle with indocyanine green (ICG), aluminum hydroxide (Al(OH)

Indexed as

Cancer VaccinesNanoparticlesOvarian NeoplasmsAluminum HydroxideAnimalsAntigens, NeoplasmCell Line, TumorFemaleHumansImmunotherapyIndocyanine GreenMicePhototherapyTumor MicroenvironmentAluminum HydroxideAntigens, NeoplasmCancer VaccinesIndocyanine GreenAntigen captureImmunogenic cell deathPhotoacoustic imagingPhotodynamic therapyPhotothermal therapyTumor immunotherapy

Identifiers

PMID36329515
PMCPMC9632083
OpenAlexW4308000338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.