Evidence map›Paper›PMID 36329498›Full record

ReviewJournal of medical case reports2022

Oral-visceral iatrogenic Kaposi sarcoma following treatment for acute lymphoblastic leukemia: a case report and review of the literature.

Richard Nyeko, Fadhil Geriga, Racheal Angom, Joyce Balagadde Kambugu

Abstract readReviewCase Reports
In one paragraph

Review in Journal of medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Kaposi's sarcoma of the larynx: case series.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Richard NyekoDepartment of Paediatric Oncology, Uganda Cancer Institute, P.O. Box 3935, Kampala, Uganda. rnyeko2@gmail.com.ORCID http://orcid.org/0000-0003-3859-349X
Fadhil GerigaDepartment of Paediatric Oncology, Uganda Cancer Institute, P.O. Box 3935, Kampala, Uganda.
Racheal AngomDepartment of Paediatric Oncology, Uganda Cancer Institute, P.O. Box 3935, Kampala, Uganda.
Joyce Balagadde KambuguDepartment of Paediatric Oncology, Uganda Cancer Institute, P.O. Box 3935, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere have hardly been any reported cases of children presenting with Kaposi sarcoma as a second malignancy following treatment for acute lymphoblastic leukemia outside a transplant setting. CASE PRESENTATION: We report a case of a 5-year-old boy of Bantu origin, which, to our knowledge, could be only the second reported case of oral-visceral Kaposi sarcoma after acute lymphoblastic leukemia treatment. The patient presented with a 1-month history of progressive, non-painful, soft tissue oral mass, 1 month after completing treatment for high-risk acute lymphoblastic leukemia. He was successfully treated for Kaposi sarcoma on a two-drug regimen (bleomycin and vincristine) with good clinical response.

conclusionVisceral Kaposi sarcoma as a second malignancy may occur after pediatric acute lymphoblastic leukemia treatment, but its rarity makes it unlikely to raise suspicion among clinicians, thus precluding early diagnosis and treatment. We recommend routine evaluation for Kaposi sarcoma lesions in children undergoing long-term surveillance following treatment for childhood acute leukemia.

Indexed as

Neoplasms, Second PrimaryPalatal NeoplasmsPrecursor Cell Lymphoblastic Leukemia-LymphomaSarcoma, KaposiChildChild, PreschoolHumansIatrogenic DiseaseMaleVincristineVincristineAcute lymphoblastic leukemiaHHV-8Kaposi sarcomaPediatric case reportSecondary malignancy

Identifiers

PMID36329498
PMCPMC9635084

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.