Evidence map›Paper›PMID 36329285›Full record

ArticlePediatric nephrology (Berlin, Germany)2023

The cost of hospitalizations for treatment of hemodialysis catheter-associated blood stream infections in children: a retrospective cohort study.

Heather L Wasik, Alicia Neu, Bradley Warady, Brendan Crawford, Troy Richardson, Heidi G De Souza, Diana Cardwell, Rebecca Ruebner, Standardizing Care to Improve Outcomes in Pediatric End-stage Kidney Disease (SCOPE) Investigators

Abstract read
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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Use of ClearGuard HD caps in pediatric hemodialysis patients.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Heather L WasikDivision of Pediatric Nephrology, SUNY Upstate Medical University, Physicians' Office Building 805, 725 Irving Avenue, Syracuse, NY, 13210, USA. wasikh@upstate.edu.ORCID http://orcid.org/0000-0002-5247-5652
Alicia NeuDivision of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bradley WaradyDivision of Pediatric Nephrology, Children's Mercy Kansas City, Kansas City, MO, USA.
Brendan CrawfordDivision of Pediatric Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Troy RichardsonChildren's Hospital Association, Lenexa, KS, USA.
Heidi G De SouzaChildren's Hospital Association, Lenexa, KS, USA.
Diana CardwellDivision of Pediatric Nephrology, Children's Health Children's Medical Center, Dallas, TX, USA.
Rebecca RuebnerDivision of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Standardizing Care to Improve Outcomes in Pediatric End-stage Kidney Disease (SCOPE) Investigators
Children's Hospital Association · USJohns Hopkins University · USChildren's Medical Center · USChildren's Mercy Hospital · USSUNY Upstate Medical University · USUniversity of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHospitalization costs for treatment of hemodialysis (HD) catheter-associated blood stream infections (CA-BSI) in adults are high. No studies have evaluated hospitalization costs for HD CA-BSI in children or identified factors associated with high-cost hospitalizations.

methodsWe analyzed 160 HD CA-BSIs from the Standardizing Care to Improve Outcomes in Pediatric End-stage Kidney Disease (SCOPE) collaborative database linked to hospitalization encounters in the Pediatric Health Information System (PHIS) database. Charge-to-cost ratios were used to convert hospitalization charges reported in PHIS database to estimated hospital costs. Generalized linear mixed modeling was used to assess the relationship between higher-cost hospitalization (cost above 50

resultsThe median (IQR) length of stay for HD CA-BSI hospitalization was 5 (3-10) days. The median (IQR) cost for HD CA-BSI hospitalization was $18,375 ($11,584-$36,266). ICU stay (aOR 5.44, 95% CI 1.62-18.26, p = 0.01) and need for a catheter procedure (aOR = 6.08, 95% CI 2.45-15.07, p < 0.001) were associated with higher-cost hospitalization.

conclusionsHospitalizations for HD CA-BSIs in children are often multiple days and are associated with substantial costs. Interventions to reduce CA-BSI may reduce hospitalization costs for children who receive chronic HD. A higher resolution version of the Graphical abstract is available as Supplementary information.

Indexed as

Catheter-Related InfectionsRenal DialysisAdultCathetersChildHospitalizationHumansRetrospective StudiesBlood stream infectionChildrenCostHemodialysis

Identifiers

PMID36329285
OpenAlexW4308102070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.