Evidence map›Paper›PMID 36329249›Full record

ReviewNature reviews. Neuroscience2022

Attractor and integrator networks in the brain.

Mikail Khona, Ila R Fiete

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed.

  1. Article
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  5. Functional neurological disorder, suggestion and virtual reality: neuroanatomical and computational perspectives.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  6. Sharp and smooth state transitions during resting state brain dynamics.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
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  14. Review
  15. Article
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  17. Review
  18. Article
  19. Article
  20. Primary cilia and neural computation.Journal of biomedical science · 2026
    Review

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mikail KhonaDepartment of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA.
Ila R FieteDepartment of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA. fiete@mit.edu.ORCID 0000-0003-4738-2539

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

In this Review, we describe the singular success of attractor neural network models in describing how the brain maintains persistent activity states for working memory, corrects errors and integrates noisy cues. We consider the mechanisms by which simple and forgetful units can organize to collectively generate dynamics on the long timescales required for such computations. We discuss the myriad potential uses of attractor dynamics for computation in the brain, and showcase notable examples of brain systems in which inherently low-dimensional continuous-attractor dynamics have been concretely and rigorously identified. Thus, it is now possible to conclusively state that the brain constructs and uses such systems for computation. Finally, we highlight recent theoretical advances in understanding how the fundamental trade-offs between robustness and capacity and between structure and flexibility can be overcome by reusing and recombining the same set of modular attractors for multiple functions, so they together produce representations that are structurally constrained and robust but exhibit high capacity and are flexible.

Indexed as

BrainNeuronsHumansMemory, Short-TermModels, NeurologicalNeural Networks, Computer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.