ArticleNature microbiology2022
Methanotrophy by a Mycobacterium species that dominates a cave microbial ecosystem.
Article in Nature microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Leveraging genome-scale metabolic models to understand aerobic methanotrophs.The ISME journal · 2024Pooled it
- A Diffusion-Driven CH4-O2 Boundary Structures Methane Oxidation and Carbon Transformation in Upland Soils.Environmental science & technology · 2026Article
- Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils.Nature microbiology · 2026Article
- Unraveling underlying mechanisms and responsible microbes of organic residue-stimulated atmospheric methane uptake in agricultural soils.FEMS microbiology ecology · 2026Article
- Acidic pH Restricts Non-Tuberculous Mycobacteria Replication.Molecular microbiology · 2026Article
- Microbially driven methane and sulfur cycling processes and coupling mechanisms in mangrove sediments.Environmental microbiome · 2026Article
- Methane-fed microbial communities enriched from field-grown rice support diverse heterotrophic bacteria.FEMS microbiology ecology · 2026Article
- Temperature Response of Aerobic Methane-Oxidizing Bacteria in Lake Sediments from King George Island, Maritime Antarctica.Microbial ecology · 2026Article
- Microbial interaction networks as climate thermometers: redefining temperature sensitivity of aerobic methanotrophy in freshwater ecosystems.npj biodiversity · 2026Article
- Methanotrophs and methane oxidation in cold wetlands: distribution, ecology, and mechanisms.ISME communications · 2026Review
- Reconstruction of 1,979 prokaryotic metagenome-assembled genomes from 37 global cave environments.Scientific data · 2025Article
- Basic assessment of microbial dynamics in large- and small-scale biofilters.Biotechnology reports (Amsterdam, Netherlands) · 2025Article
- Microbial aerotrophy enables continuous primary production in diverse cave ecosystems.Nature communications · 2025Article
- Intensive rice cropping drives shifts in abundance, activity, and assembly of root-associated methanotrophic community.FEMS microbiology ecology · 2025Article
- Expansion of aerobic methanotrophy to the phylum of Actinomycetota and its environmental implications.Applied and environmental microbiology · 2025Article
- Microbial ecology of acidic, biogenic gypsum: community structure and distribution of extremophiles on freshly formed and relict sulfate deposits in a hydrogen sulfide-rich cave.Applied and environmental microbiology · 2025Article
- Characterization of Mycobacterium antarcticum sp. nov., a psychrotolerant member of the genus Mycobacterium isolated from Antarctic soil.Scientific reports · 2025Article
- Diversity and distribution of the lanthanome in aerobic methane-oxidising bacteria.Environmental microbiome · 2025Article
- First isolation of a methanotrophicApplied and environmental microbiology · 2025Article
- Microbial and Geochemical Variability in Sediments and Biofilms from Italian Gypsum Caves.Microbial ecology · 2025Article
Corrections and comments
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Authors and funding
21 authors at 9 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
So far, only members of the bacterial phyla Proteobacteria and Verrucomicrobia are known to grow methanotrophically under aerobic conditions. Here we report that this metabolic trait is also observed within the Actinobacteria. We enriched and cultivated a methanotrophic Mycobacterium from an extremely acidic biofilm growing on a cave wall at a gaseous chemocline interface between volcanic gases and the Earth's atmosphere. This Mycobacterium, for which we propose the name Candidatus Mycobacterium methanotrophicum, is closely related to well-known obligate pathogens such as M. tuberculosis and M. leprae. Genomic and proteomic analyses revealed that Candidatus M. methanotrophicum expresses a full suite of enzymes required for aerobic growth on methane, including a soluble methane monooxygenase that catalyses the hydroxylation of methane to methanol and enzymes involved in formaldehyde fixation via the ribulose monophosphate pathway. Growth experiments combined with stable isotope probing using
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.