Evidence map›Paper›PMID 36329151›Full record

ArticleScientific reports2022

Synthesis, characterization, and radiosynthesis of fluorine-18-AVT-011 as a Pgp chemoresistance imaging marker.

Pardeep Kumar, Riptee Thakur, Pratap Chandra Acharya, Hosahalli K Mohan, U N Pallavi, Divya Maheshwari, Afsal Mohammed K M, Aishwarya Kumar, Sridhar Goud Nerella, Raman Kumar Joshi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. India's Growing Nuclear Medicine Infrastructure and Emergence of Radiotheranostics in Cancer Care: Associated Challenges and the Opportunities to Collaborate.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Pardeep KumarDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India. pardeep1182@gmail.com.
Riptee ThakurDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
Pratap Chandra AcharyaDepartment of Pharmacy, Tripura University (A Central University), Suryamaninagar, Tripura (W), India.
Hosahalli K MohanDepartment of Nuclear Medicine, Sri Shankara Cancer Hospital & Research Centre, Bengaluru, Karnataka, India.
U N PallaviDepartment of Nuclear Medicine, Sri Shankara Cancer Hospital & Research Centre, Bengaluru, Karnataka, India.
Divya MaheshwariAvaant Imaging, Lexington, MA, USA.
Afsal Mohammed K MEsente Healthcare, Bengaluru, Karnataka, India.
Aishwarya KumarDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
Sridhar Goud NerellaDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
Raman Kumar JoshiDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
Manoj KumarDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
Chandana NagarajDepartment of Neuroimaging and Interventional Radiology, NIMHANS, Bengaluru, Karnataka, India.
National Institute of Mental Health and Neurosciences · INHCG Cancer Hospital · INHealthcare Global Enterprises · INSri Shankara Cancer Hospital and Research CenterTripura University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

P-glycoprotein (Pgp) is the most studied ATP-binding cassette (ABC) efflux transporter and contributes to chemoresistance. A few tracers have been developed to detect the in-vivo status of chemoresistance using positron emission tomography (PET) imaging. In our study, we have synthesized labeled AVT-011 with fluorine-18 (

Indexed as

Drug Resistance, NeoplasmPositron Emission Tomography Computed TomographyAnimalsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily B, Member 1Fluorine RadioisotopesMicePositron-Emission TomographyRadiopharmaceuticalsTissue DistributionATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily B, Member 1Fluorine-18Fluorine RadioisotopesRadiopharmaceuticals

Identifiers

PMID36329151
PMCPMC9633701
OpenAlexW4308484605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.