Evidence map›Paper›PMID 36329042›Full record

ArticleScientific reports2022

Myocardial infarction risk is increased by periodontal pathobionts: a cross-sectional study.

C Joshi, A Mezincescu, M Gunasekara, A Rudd, H Botchorichvili, S Sabir, C Dospinescu, A Noman, D Hogg, G Cherukara and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Combined oral and peripheral blood detection ofJournal of oral microbiology · 2026
    Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

C JoshiInstitute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZR, UK.
A MezincescuDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
M GunasekaraDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
A RuddDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
H BotchorichviliInstitute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZR, UK.
S SabirInstitute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZR, UK.
C DospinescuDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
A NomanDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
D HoggDepartment of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK.
G CherukaraInstitute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZR, UK.
D McLernonMedical Statistics Team, Institute of Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.
K Hijazi *Institute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZR, UK. k.hijazi@abdn.ac.uk.ORCID 0000-0002-8589-2129
D Dawson *Department of Cardiology and Institute of Dentistry, School of Medicine, University of Aberdeen, Level 1, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK. dana.dawson@abdn.ac.uk.ORCID 0000-0003-2815-4469
University of Aberdeen · GB

Funding

British Heart Foundation CS/17/4/32960British Heart Foundation FS/RTF/20/30009British Heart Foundation NH/19/1/34595British Heart Foundation PG/15/88/31780British Heart Foundation PG/17/64/33205British Heart Foundation PG/18/35/33786
6 · The paper itself

Abstract

To establish the role of periodontal pathobionts as a risk factor for myocardial infarction, we examined the contribution of five periodontal pathobionts and their virulence genes' expressions to myocardial injury (Troponin-I) and coronary artery disease burden (SYNTAX-I scores) using hierarchical linear regression. Pathobiont loads in subgingival-plaques and intra-coronary-thrombi were compared. Troponin-I release increased with one 16S rRNA gene copy/ng DNA of Porphyromonas gingivalis (β = 6.8 × 10

Indexed as

Myocardial InfarctionTroponin ICross-Sectional StudiesDNAHumansPorphyromonas gingivalisRNA, Ribosomal, 16SDNARNA, Ribosomal, 16STroponin I

Identifiers

PMID36329042
PMCPMC9633823
OpenAlexW4308482768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.