Evidence map›Paper›PMID 36328992›Full record

ArticleKidney research and clinical practice2023

Weight change and risk of depression in patients with diabetic kidney disease: a nationwide population-based study.

Hong Sang Choi, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Sang Heon Suh, Minah Kim, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney research and clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hong Sang ChoiDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Bongseong KimDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
Kyung-Do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
Tae Ryom OhDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Sang Heon SuhDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Minah KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Chang Seong KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Eun Hui BaeDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Seong Kwon MaDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Chonnam National University · KRSoongsil University · KR

Funding

Chonnam National University Hospital Biomedical Research Institute BCRI22080National Research Foundation of Korea NRF-2022R1C1C1007573
6 · The paper itself

Abstract

backgroundSeveral studies have reported that depression is prevalent in patients with diabetes or chronic kidney disease. However, the relationship between weight changes and the risk of depression has not been elucidated in patients with diabetic kidney disease (DKD).

methodsFrom the Korean National Health Insurance Service database, we selected 67,866 patients with DKD and body weight data from two consecutive health examinations with a 2-year interval between 2009 and 2012. Weight change over 2 years was categorized into five groups: ≥-10%, <-10% to ≥-5%, <-5% to <5%, ≥5% to <10%, and ≥10%. The occurrence of depression was monitored via the codes of International Statistical Classification of Diseases, 10th revision through the end of 2018.

resultsDuring the 5.24-year follow-up, 17,023 patients with DKD developed depression. Weight change and the risk of depression had a U-shaped relationship: patients with ≥-10% weight change (hazard ratio [HR], 1.12) and those with ≥10% weight change (HR, 1.11) showed higher HRs for depression than those with <-5% to <5% weight change, even after adjusting for several confounding factors. In the subgroup analyses, the risk of depression tended to increase as weight gain or weight loss increased in all subgroups.

conclusionBoth weight loss and weight gain increased the risk of depression in patients with DKD.

Indexed as

DepressionDiabetic nephropathiesRiskWeight change

Identifiers

PMID36328992
PMCPMC9902731
OpenAlexW4294926317

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.