Evidence map›Paper›PMID 36328575›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Two Cases of Encephalitis without Anti-N-methyl-D-aspartate Receptor Antibody Successfully Treated with Ovarian Teratoma Resection and Immunotherapy.

Marie Morooka, Akiyuki Hiraga, Keiko Tanaka, Satoko Yoshizaki, Kyosuke Koide, Satoshi Kuwabara

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marie MorookaDepartment of Neurology, Chiba Rosai Hospital, Japan.
Akiyuki HiragaDepartment of Neurology, Chiba Rosai Hospital, Japan.
Keiko TanakaBrain Research Institute, Niigata University, Japan.
Satoko YoshizakiDepartment of Neurology, Chiba Rosai Hospital, Japan.
Kyosuke KoideDepartment of Neurology, Chiba Rosai Hospital, Japan.
Satoshi KuwabaraDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Chiba Rosai Hospital · JPChiba University · JPNiigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder sometimes accompanied by ovarian teratoma. However, the concept of encephalitis without anti-NMDAR antibodies successfully treated with ovarian teratoma resection and immunotherapy has not been established. We herein report two such cases. Case 1 exhibited delayed magnetic resonance imaging abnormalities in the thalamus and basal ganglia, despite clinical improvement. Case 2 presented with brainstem encephalitis similar to Bickerstaff's encephalitis. Although both patients tested negative for anti-NMDAR antibodies, the recovery of the neurological function and good prognosis following tumor resection with immunotherapy indicated a close association between these diseases and ovarian teratoma.

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisOvarian NeoplasmsTeratomaFemaleHumansImmunotherapyReceptors, Amino AcidReceptors, N-Methyl-D-Aspartateaspartic acid receptorReceptors, Amino AcidReceptors, N-Methyl-D-Aspartateanti-NMDAR encephalitisBickerstaff's encephalitisovarian teratomaseronegative

Identifiers

PMID36328575
PMCPMC10332985
OpenAlexW4308011076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.