Evidence map›Paper›PMID 36328490›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Fast and Accurate Amyloid Brain PET Quantification Without MRI Using Deep Neural Networks.

Seung Kwan Kang, Daewoon Kim, Seong A Shin, Yu Kyeong Kim, Hongyoon Choi, Jae Sung Lee

Abstract readMulticenter Study
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. AI-enhanced Centiloid quantification of amyloid PET images.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  9. Artificial Intelligence-Powered Quantification of Flortaucipir PET for Detecting Tau Pathology.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
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  12. Revisiting Centiloids using AI.Research square · 2025
    Article
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  16. ImprovingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seung Kwan KangBrightonix Imaging Inc., Seoul, Korea.
Daewoon KimInterdisciplinary Program of Bioengineering, Seoul National University, Seoul, Korea.
Seong A ShinBrightonix Imaging Inc., Seoul, Korea.
Yu Kyeong KimDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea; and.
Hongyoon ChoiInstitute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.
Jae Sung LeeBrightonix Imaging Inc., Seoul, Korea; jaes@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper proposes a novel method for automatic quantification of amyloid PET using deep learning-based spatial normalization (SN) of PET images, which does not require MRI or CT images of the same patient. The accuracy of the method was evaluated for 3 different amyloid PET radiotracers compared with MRI-parcellation-based PET quantification using FreeSurfer.

Indexed as

Alzheimer DiseaseAmyloidAmyloidogenic ProteinsAniline CompoundsBenzothiazolesBrainHumansMagnetic Resonance ImagingNeural Networks, ComputerPositron-Emission TomographyStilbenes4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbeneAmyloidAmyloidogenic ProteinsAniline CompoundsBenzothiazolesflutemetamolStilbenesamyloid PETdeep learningquantificationspatial normalization

Identifiers

PMID36328490
PMCPMC10071781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.