Evidence map›Paper›PMID 36328383›Full record

ArticleBMJ open2022

Best Case/Worst Case: protocol for a multisite randomised clinical trial of a scenario planning intervention for patients with kidney failure.

Karlie Haug, Anne Buffington, Amy Zelenski, Bret M Hanlon, Lily Stalter, Kristine L Kwekkeboom, Paul Rathouz, Amar D Bansal, Katharine Cheung, Deidra Crews and 12 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04466865 (Best Case/Worst Case), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04466865 nacompletednot on this map

Best Case/Worst Case: A Multisite Randomized Clinical Trial of Scenario Planning for Patients With End-Stage Kidney Disease

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2020 to 2026Enrolled407ConditionsPalliative Care, Kidney Failure, Chronic, Decision Making, Decision Support TechniquesArmsBest Case/Worst Case communication tool training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Global, regional, and national burden of glaucoma, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 1 country.

Karlie HaugDepartment of Surgery, University of Wisconsin, Madison, Wisconsin, USA khaug@uwhealth.org.ORCID 0000-0002-2445-0802
Anne BuffingtonDepartment of Surgery, University of Wisconsin, Madison, Wisconsin, USA.
Amy ZelenskiDepartment of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-2096-8567
Bret M HanlonUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-4517-1204
Lily StalterDepartment of Surgery, University of Wisconsin, Madison, Wisconsin, USA.
Kristine L KwekkeboomUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Paul RathouzDepartment of Biostatistics & Medical Informatics, University of Wisconsin, Madison, WI, USA.
Amar D BansalDivision of Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Katharine CheungDivision of Nephrology, University of Vermont, Burlington, Vermont, USA.
Deidra CrewsDivision of Nephrology, Johns Hopkins University, Baltimore, Maryland, USA.
Rebecca FrazierDivision of Nephrology, Northwestern Memorial HealthCare Corp, Chicago, Illinois, USA.
Holly KoncickiDivision of Nephrology, Mount Sinai Health System, New York, New York, USA.
Daniel LamDivision of Nephrology, University of Washington, Seattle, Washington, USA.
Alvin MossSection of Nephrology, West Virginia University, Morgantown, West Virginia, USA.
Maya RaoDivision of Nephrology, Columbia University, New York, New York, USA.
Dawn F WolfgramDivision of Nephrology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jeniann YiDepartment of Surgery, University of Colorado Health, Aurora, Colorado, USA.
Carrie BrillUniversity of Colorado, Denver, Colorado, USA.
Rachael KendrickUniversity of Colorado, Denver, Colorado, USA.
Toby C CampbellDepartment of Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Roy JhagrooDepartment of Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Margaret SchwarzeDepartment of Surgery, University of Wisconsin, Madison, Wisconsin, USA.
University of Wisconsin–Madison · USUniversity of Colorado Denver · USColumbia University · USJohns Hopkins University · USMedical College of Wisconsin · USMount Sinai Health System · USNorthwestern Medicine · USUniversity of Colorado Health · USUniversity of Pittsburgh · USUniversity of Vermont · USUniversity of Washington · USWest Virginia University · US

Funding

Palliative Care Research Cooperative Group (PCRC): Refinement and ExpansionU2CNR014637 · NINR · UNIVERSITY OF COLORADO DENVER · PI RITCHIE, CHRISTINE S · 2018 to 2022
$8.6M
Best Case/Worst Case: A Multisite Randomized Clinical Trial of Scenario Planning for Patients with End-Stage Kidney DiseaseR01AG065365 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI SCHWARZE, MARGARET · 2020 to 2024
$3.0M
Vascular Surgery Research Training ProgramT32HL110853 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MATSUMURA, JON STEVEN · 2012 to 2021
$2.6M
NHLBI NIH HHS T32 HL110853NIA NIH HHS R01 AG065365NINR NIH HHS U2C NR014637
6 · The paper itself

Abstract

introductionGiven the burdens of treatment and poor prognosis, older adults with kidney failure would benefit from improved decision making and palliative care to clarify goals, address symptoms, and reduce unwanted procedures. Best Case/Worst Case (BC/WC) is a communication tool that uses scenario planning to support patients' decision making. This article describes the protocol for a multisite, cluster randomised trial to test the effect of training nephrologists to use the BC/WC communication tool on patient receipt of palliative care, and quality of life and communication. METHODS AND ANALYSIS: We are enrolling attending nephrologists, at 10 study sites in the USA, who see outpatients with advanced chronic kidney disease considering dialysis. We aim to enrol 320 patients with an estimated glomerular filtration rate of ≤24 mL/min/1.73 m ETHICS AND DISSEMINATION: Approvals have been granted by the Institutional Review Board at the University of Wisconsin (ID: 2022-0193), with each study site ceding review to the primary IRB. All nephrologists will be consented and given a copy of the consent form. No patients or caregivers will be recruited or consented until their nephrology provider has chosen to participate in the study. Results will be disseminated via submission for publication in a peer-reviewed journal and at national meetings. TRIAL REGISTRATION NUMBER: NCT04466865.

Indexed as

Quality of LifeRenal InsufficiencyAgedCommunicationHumansMiddle AgedPalliative CareRandomized Controlled Trials as TopicRenal DialysisAdult nephrologyAdult palliative careChronic renal failureDialysisEnd stage renal failureMEDICAL ETHICS

Identifiers

PMID36328383
PMCPMC9639110
OpenAlexW4308451472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.