Evidence map›Paper›PMID 36328182›Full record

ArticleVirologica Sinica2022

Clinical and immunological features of convalescent pediatric patients infected with the SARS-CoV-2 Omicron variant in Tianjin, China.

Jing-Yu Wang, Tian-Ning Li, Chun-Lei Zhou, Jie Zhao, Meng Wang, Yuan Wang, Yan Jiang, He-Nan Dong, Qian-Ru Qi, Hong Mu

Abstract read
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Article in Virologica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing-Yu WangDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Tian-Ning LiDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Chun-Lei ZhouDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Jie ZhaoDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Meng WangDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Yuan WangDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
Yan JiangDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China.
He-Nan DongThe First Central Clinical College, Tianjin Medical University, Tianjin, 300192, China.
Qian-Ru QiDepartment of Clinical Lab, Tianjin Children's Hospital, Tianjin, 300074, China.
Hong MuDepartment of Clinical Lab, Tianjin First Central Hospital, Tianjin, 300192, China. Electronic address: tjmuhong@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 has spread surprisingly fast worldwide, and new variants continue to emerge. Recently, the World Health Organization acknowledged a new mutant strain "Omicron", with children were accounting for a growing share of COVID-19 cases compared with other mutant strains. However, the clinical and immunological characteristics of convalescent pediatric patients after Omicron infection were lacking. In this study, we comparatively analyzed the clinical data from pediatric patients with adult patients or healthy children and the effects of SARS-CoV-2 vaccine on the clinical and immune characteristics in convalescent pediatric patients. Our results indicated that convalescent pediatric patients had unique clinical and immune characteristics different from those of adult patients or healthy children, and SARS-CoV-2 vaccination significantly affected on the clinical and immune characteristics and the prevention of nucleic acid re-detectable positive (RP) in convalescent patients. Our study further deepens the understanding of the impact of Omicron on the long-term health of pediatric patients and provides a valuable reference for the prevention and treatment of children infected with Omicron.

Indexed as

COVID-19SARS-CoV-2AdultChildChinaCOVID-19 VaccinesHumansCOVID-19 VaccinesClinical characteristicsCOVID-19Pediatric patientsSARS-CoV-2 Omicron variantSARS-CoV-2 vaccine

Identifiers

PMID36328182
PMCPMC9621613

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.