Evidence map›Paper›PMID 36328163›Full record

ArticleBrain, behavior, and immunity2023

Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke.

Kathiresh Kumar Mani, Yumna El-Hakim, Taylor E Branyan, Nadia Samiya, Sivani Pandey, Maria T Grimaldo, Ali Habbal, Anna Wertz, Farida Sohrabji

Open access · hybridAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  11. Article
  12. Th17 Cells and IL-17A in Ischemic Stroke.Molecular neurobiology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. The aging ovary impairs acute stroke outcomes.Journal of neuroinflammation · 2023
    Article
  17. Review
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kathiresh Kumar ManiWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States; Texas A&M Institute for Neuroscience, Texas A&M University, Bryan, TX 77807, United States.
Yumna El-HakimWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Taylor E BranyanWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States; Texas A&M Institute for Neuroscience, Texas A&M University, Bryan, TX 77807, United States.
Nadia SamiyaWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Sivani PandeyWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Maria T GrimaldoWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Ali HabbalWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Anna WertzWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States.
Farida SohrabjiWomen's Health in Neuroscience Program, Department of Neuroscience and Experimental Therapeutics, College of Medicine, Mail Stop 1359 | 8447 Riverside Pkwy, Bryan, TX 77807-3260, United States; Texas A&M Institute for Neuroscience, Texas A&M University, Bryan, TX 77807, United States. Electronic address: f-sohrabji@tamu.edu.
Texas A&M Health Science Center · USTexas A&M University · US

Funding

Epigenetics of the Aging Astrocyte: Implications for StrokeRF1AG042189 · NIA · TEXAS A&M UNIVERSITY · PI SOHRABJI, FARIDA · 2018 to 2018
$2.8M
Targeting the gut for stroke neuroprotection; IGF-1 modulation of the blood-gut barrierRF1NS119872 · NINDS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI BAKE, SHAMEENA, SOHRABJI, FARIDA · 2022 to 2022
$1.7M
Targeting the Gut for Stroke Neuroprotection; IGF-1 Modulation of the Blood-Gut BarrierR01NS119872 · NINDS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Shameena Bake, Farida Sohrabji · 2025 to 2026
$1.1M
Role of Astrocytic miR-20a-3p as a Potential Therapeutic for Ischemic StrokeF31NS118970 · NINDS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI BRANYAN, TAYLOR · 2021 to 2023
$106k
NIA NIH HHS RF1 AG042189NINDS NIH HHS F31 NS118970NINDS NIH HHS R01 NS119872NINDS NIH HHS RF1 NS119872
6 · The paper itself

Abstract

Almost 2/3

Indexed as

Motor DisordersPersons with DisabilitiesStrokeAnimalsHumansRatsStem Cell TransplantationIL17Intestinal epithelial stem cellsLgr5+OrganoidsPost stroke cognitive impairmentStrokeTransplant

Identifiers

PMID36328163
PMCPMC11906171
OpenAlexW4307906567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.