ArticleJournal of the American College of Cardiology2023
Implementation of High-Sensitivity Cardiac Troponin Assays in the United States.
Article in Journal of the American College of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Ischemic heart disease mortality with documented tobacco use in the United States, 1999-2023: a nationwide population-based analysis.Archives of public health = Archives belges de sante publique · 2026Article
- Clinical and Economic Implications of High-Sensitivity Troponin-Informed Admission Strategies in Non-AMI Chest Pain.Journal of cardiovascular development and disease · 2026Article
- Introduction of High-Sensitivity Troponin Assay to Rural Tertiary Care Medical Center: Impact on Subsequent Cardiac Diagnostic Testing.Diagnostics (Basel, Switzerland) · 2026Article
- Trends in post-discharge major adverse cardiovascular events following myocardial infarction: Insights from the veterans healthcare administration.American journal of preventive cardiology · 2026Article
- Article
- Implementation of High-Sensitivity Troponin for Early Rule-Out of Acute Myocardial Infarction in Emergency Department.American journal of medicine open · 2025Article
- Implementation of a High-Sensitivity Troponin Assay and Its Association With Resource Utilization in Patients With Suspected Acute Coronary Syndrome.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Revisiting High-Sensitivity Cardiac Troponin Abnormal Baseline Cutoffs: Implications for AMI Diagnosis in the Emergency Department.Journal of clinical medicine · 2025Article
- Emergency Department Implementation of a Multimodal Electronic Health Record-Integrated Clinical Intervention for High-Sensitivity Troponin Testing Increases Diagnostic Efficiency.Journal of the American College of Emergency Physicians open · 2025Article
- Ischemic heart disease-related mortality trends in the United States (1999-2020) and prediction using machine learning.Annals of medicine and surgery (2012) · 2025Review
- Real-World Clinical Impact of High-Sensitivity Troponin for Chest Pain Evaluation in the Emergency Department.Journal of the American Heart Association · 2025Article
- High-Sensitivity Cardiac Troponin Assays: From Implementation to Resource Utilization and Cost Effectiveness.The journal of applied laboratory medicine · 2025Review
- Clinical Outcomes, Healthcare Utilization, and Cost Following Implementation of a High-Sensitivity Cardiac Troponin Assay.Clinical cardiology · 2025Article
- Machine learning in point-of-care testing: innovations, challenges, and opportunities.Nature communications · 2025Review
- National cost savings, operational and safety benefits from use of magnetocardiography in the assessment of emergency department chest pain patients.American heart journal plus : cardiology research and practice · 2024Article
- Article
- Delta troponin does not distinguish acute coronary syndrome in emergency department patients with renal impairment and an initial positive troponin.Journal of the American College of Emergency Physicians open · 2024Article
- Improved Utilization of Serial Testing Without Increased Admissions after Implementation of High-Sensitivity Troponin I: a Controlled Retrospective Cohort Study.Journal of general internal medicine · 2024Article
- Serial troponin-I and long-term outcomes in subjects with suspected acute coronary syndrome.European journal of preventive cardiology · 2024Article
- The significance of historical troponin elevation in acute heart failure: Not as reassuring as previously assumed.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023Article
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Authors and funding
15 authors at 11 institutions in 1 country.
Funding
Abstract
backgroundFew data exist regarding the implementation of high-sensitivity cardiac troponin (hs-cTn) assays in the United States since their approval.
objectivesThis study sought to explore trends in hs-cTn assay implementation over time and assess the association of their use with in-hospital cardiac testing and outcomes.
methodsThe study examined trends in implementation of hs-cTn assays among participating hospitals in the National Cardiovascular Data Registry Chest Pain-MI [Myocardial Infarction] Registry from January 1, 2019 through September 30, 2021. Associations among hs-cTn use, use of in-hospital diagnostic imaging, and patient outcomes were assessed using generalized estimating equation models with logistic or gamma distributions.
resultsAmong 550 participating hospitals (N = 251,000), implementation of hs-cTn assays increased from 3.3% in the first quarter of 2019 to 32.6% in the third quarter of 2021 (P
conclusionsImplementation of hs-cTn among U.S. hospitals is increasing, but most U.S. hospitals continue to use less sensitive assays. The use of hs-cTn was associated with modestly shorter length of stay, greater use of echocardiography for NSTE-ACS, and less use of invasive angiography among low-risk patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.