Evidence map›Paper›PMID 36328100›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2023

Pharmacokinetics and Pharmacodynamics of Apixaban in Nephrotic Syndrome: Findings From a Phase 1a Trial.

Vimal K Derebail, Jing Zhu, Matthew L Crawford, Julia R Garnier, Karlyn A Martin, Sarah Skinner, Tejendra Patel, Anne Froment, Margaret R Sketch, Andy H Szeto and 7 more

Open access · bronzeAbstract readClinical Trial, Phase ILetter
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  3. Renal Vein Thrombosis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Vimal K DerebailUNC Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: vimal_derebail@med.unc.edu.
Jing ZhuDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Matthew L CrawfordLaboratory Corporation of America, Burlington, North Carolina.
Julia R GarnierLaboratory Corporation of America, Burlington, North Carolina.
Karlyn A MartinDivision of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Evanston, Illinois.
Sarah SkinnerUNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Tejendra PatelDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Anne FromentUNC Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Margaret R SketchDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Andy H SzetoDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Sheel M PatelDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Chad D TorriceDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Stefan TiefenbacherColorado Coagulation, Laboratory Corporation of America, Englewood, Colorado.
Dorothy M AdcockLaboratory Corporation of America, Burlington, North Carolina.
Russell P GrantLaboratory Corporation of America, Burlington, North Carolina.
Nigel S KeyUNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Division of Hematology, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Daniel J CronaDivision of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Pharmacy, UNC Medical Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: daniel.crona@unc.edu.
University of North Carolina at Chapel Hill · USLeco Corporation (United States) · USNorthwestern University · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Research Training in Hematology at UNC Chapel HillT32HL007149 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Nigel S. Key · 1985 to 2026
$8.6M
NCATS NIH HHS UL1 TR002489NHLBI NIH HHS T32 HL007149NIDDK NIH HHS L30 DK123764
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Nephrotic SyndromeFactor Xa InhibitorsHumansPyrazolesPyridonesapixabanFactor Xa InhibitorsPyrazolesPyridones

Identifiers

PMID36328100
PMCPMC12038909
OpenAlexW4308025602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.