ArticleEndocrinology and metabolism (Seoul, Korea)2022
Updates on Paget's Disease of Bone.
Article in Endocrinology and metabolism (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 16 citations in OpenAlex.
- Genetic Bone Diseases: A Scoping Review of Pathology, Symptoms, Diagnosis, Treatment, and New Horizons.Advanced genetics (Hoboken, N.J.) · 2026Review
- Paget's Disease Unveiled in a Primary Care Setting: A Case of High Alkaline Phosphatase.Cureus · 2026Article
- Paget's disease of bone: pathogenesis, ocular manifestations, and therapeutic strategies.Orphanet journal of rare diseases · 2026Review
- Synergistic application of concentrated growth factor and bone perforation technique in bisphosphonate-related-osteonecrosis of the jaw.BMC oral health · 2026Article
- Paget-like bone remodeling disorder in a red-tailed boa (Journal of veterinary science · 2026Article
- Paget's disease of bone in a North African population: clinical, imaging, and therapeutic insights from a Moroccan case series.Clinical rheumatology · 2026Review
- Paget's Disease of Bone and Normocalcemic Variant of Primary Hyperparathyroidism in an Osteoporotic Male: Exceptional Coexistence.Reports (MDPI) · 2025Article
- The role of γδ T cells in flavivirus infections: Insights into immune defense and therapeutic opportunities.PLoS neglected tropical diseases · 2025Review
- Identifying Paget’s Disease in the Elderly-an oft-missed DiagnosisBalkan medical journal · 2025Article
- Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation.Current drug targets · 2025Review
- Phalange osteolysis present as the initial manifestation of sarcoidosis in a young female.SAGE open medical case reports · 2025Article
- Effects of Erythropoietin-Promoted Fracture Healing on Bone Turnover Markers in Cats.Journal of functional biomaterials · 2024Article
- Paget's disease of bone in the patient presented with a bowed leg.Clinical case reports · 2023Article
- Newly Diagnosed Monostotic Paget's Disease of Bone during Living Kidney Donor Candidate Evaluation.Biomedicines · 2023Article
- Educational Case: Paget disease of bone.Academic pathologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paget's disease of the bone is a prevalent bone disease characterized by disorganized bone remodeling; however, it is comparatively uncommon in East Asian countries, including China, Japan, and Korea. The exact cause still remains unknown. In genetically susceptible individuals, environmental triggers such as paramyxoviral infections are likely to cause the disease. Increased osteoclast activity results in increased bone resorption, which attracts osteoblasts and generates new bone matrix. Fast bone resorption and formation lead to the development of disorganized bone tissue. Increasing serum alkaline phosphatase or unique radiographic lesions may serve as the diagnostic indicators. Common symptoms include bone pain, bowing of the long bones, an enlarged skull, and hearing loss. The diagnosis is frequently confirmed by radiographic and nuclear scintigraphy of the bone. Further, bisphosphonates such as zoledronic acid and pamidronate are effective for its treatment. Moreover, biochemical monitoring is superior to the symptoms as a recurrence indicator. This article discusses the updates of Paget's disease of bone with a clinical case.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.