Evidence map›Paper›PMID 36327864›Full record

ArticlePsychiatry research. Neuroimaging2022

Neuroeconomic predictors of smoking cessation outcomes: A preliminary study of delay discounting in treatment-seeking adult smokers.

Michael Amlung, Max M Owens, Tegan Hargreaves, Joshua C Gray, Cara M Murphy, James MacKillop, Lawrence H Sweet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research. Neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael AmlungDepartment of Applied Behavioral Science, University of Kansas, Lawrence, KS, United States of America; Cofrin Logan Center for Addiction Research and Treatment, University of Kansas, Lawrence, KS, United States of America. Electronic address: mamlung@ku.edu.
Max M OwensDepartment of Psychiatry and Behavioural Neuroscience, McMaster University, Hamilton, ON Canada; Peter Boris Centre for Addictions Research, McMaster University, Hamilton, ON, Canada.
Tegan HargreavesPeter Boris Centre for Addictions Research, McMaster University, Hamilton, ON, Canada.
Joshua C GrayDepartment of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, United States of America.
Cara M MurphyBehavioral and Social Sciences, Brown University, Providence, RI, United States of America.
James MacKillopDepartment of Psychiatry and Behavioural Neuroscience, McMaster University, Hamilton, ON Canada; Peter Boris Centre for Addictions Research, McMaster University, Hamilton, ON, Canada.
Lawrence H SweetDepartment of Psychology, University of Georgia, Athens, GA United States of America.

Funding

Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol ValueR01AA027255 · NIAAA · UNIVERSITY OF KANSAS LAWRENCE · PI AMLUNG, MICHAEL T. · 2019 to 2023
$1.2M
Neuroimaging approaches to improve prediction of relapse during smoking cessationR21DA031269 · NIDA · UNIVERSITY OF GEORGIA · PI SWEET, LAWRENCE H · 2012 to 2013
$384k
NIAAA NIH HHS R01 AA027255NIDA NIH HHS R21 DA031269
6 · The paper itself

Abstract

Large proportions of smokers are unsuccessful in evidence-based smoking cessation treatment and identifying prognostic predictors may inform improvements in treatment. Steep discounting of delayed rewards (delay discounting) is a robust predictor of poor smoking cessation outcome, but the underlying neural predictors have not been investigated. Forty-one treatment-seeking adult smokers completed a functional magnetic resonance imaging (fMRI) delay discounting paradigm prior to initiating a 9-week smoking cessation treatment protocol. Behavioral performance significantly predicted treatment outcomes (verified 7-day abstinence, n = 18; relapse, n = 23). Participants in the relapse group exhibited smaller area under the curve (d = 1.10) and smaller AUC was correlated with fewer days to smoking relapse (r = 0.56, p < 0.001) Neural correlates of discounting included medial and dorsolateral prefrontal cortex, posterior cingulate, precuneus and anterior insula, and interactions between choice type and relapse status were present for the dorsolateral prefrontal cortex, precuneus and the striatum. This initial investigation implicates differential neural activity in regions associated with frontal executive and default mode activity, as well as motivational circuits. Larger samples are needed to improve the resolution in identifying the neural underpinnings linking steep delay discounting to smoking cessation.

Indexed as

Delay DiscountingSmoking CessationAdultHumansRecurrenceRewardSmokersDelayed reward discountingNeuroeconomicsNicotine dependenceTreatment response

Identifiers

PMID36327864
PMCPMC9729436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.