Evidence map›Paper›PMID 36327755›Full record

ArticleThe American journal of emergency medicine2023

Non-rebreather mask and low-flow nasal cannula vs high-flow nasal cannula in severe COVID-19 pneumonia in the emergency department.

Muhammad Khidir Mohd Kamil, Khadijah Poh Yuen Yoong, Abdul Muhaimin Noor Azhar, Aida Bustam, Ahmad Hariz Abdullah, Mohd Hafyzuddin Md Yusuf, Aliyah Zambri, Ahmad Zulkarnain Ahmad Zahedi, Hidayah Shafie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Article
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  6. Global emergency medicine: A scoping review of the literature from 2023.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Muhammad Khidir Mohd KamilDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: presisoc90@gmail.com.
Khadijah Poh Yuen YoongDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: khadijah.poh@ummc.edu.my.
Abdul Muhaimin Noor AzharDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: muhaimin@um.edu.my.
Aida BustamDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: aidabustam@um.edu.my.
Ahmad Hariz AbdullahEmergency and Trauma Department, Kuala Lumpur, Hospital, Kuala Lumpur, Malaysia.
Mohd Hafyzuddin Md YusufDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: hafyzuddin@ummc.edu.my.
Aliyah ZambriDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: nuraliyah@ummc.edu.my.
Ahmad Zulkarnain Ahmad ZahediDepartment of Emergency Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address: ahmadzulkarnain@ummc.edu.my.
Hidayah ShafieEmergency and Trauma Department, Kuala Lumpur, Hospital, Kuala Lumpur, Malaysia.
University of Malaya · MYHospital Kuala Lumpur · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the effectiveness of non-rebreather mask combined with low-flow nasal cannula (NRB + NC) compared to high-flow nasal cannula (HFNC) in improving oxygenation in patients with COVID-19-related hypoxemic respiratory failure (HRF).

methodsThis retrospective study was conducted in emergency departments of two tertiary hospitals from June 1 to August 31, 2021. Consecutive patients aged >18 years admitted for COVID-19-related HRF (World Health Organization criteria: confirmed COVID-19 pneumonia with respiratory rate > 30 breaths/min, severe respiratory distress, or peripheral oxygen saturation < 90% on room air) requiring NRB + NC or HFNC were screened for enrollment. Primary outcome was improvement of partial pressure arterial oxygen (PaO

resultsAmong the 110 patients recruited, 52 (47.3%) were treated with NRB + NC, and 58 (52.7%) with HFNC. There were significant improvements in patients' PaO

conclusionHFNC may be beneficial in COVID-19 HRF. NRB + NC is a viable alternative, especially in resource-limited settings, given similar improvement in oxygenation at two hours, and no significant differences in long-term outcomes. The effectiveness of NRB + NC needs to be investigated by a powered randomized controlled trial.

Indexed as

CannulaCOVID-19Emergency Service, HospitalHumansRetrospective StudiesCOVID-19High-flow nasal cannulaHypoxemic respiratory failureNon-rebreather maskOxygen therapy

Identifiers

PMID36327755
PMCPMC9578968
OpenAlexW4306767661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.