Evidence map›Paper›PMID 36326868›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2023

Joint EANM/SNMMI guideline on radiomics in nuclear medicine : Jointly supported by the EANM Physics Committee and the SNMMI Physics, Instrumentation and Data Sciences Council.

M Hatt, A K Krizsan, A Rahmim, T J Bradshaw, P F Costa, A Forgacs, R Seifert, A Zwanenburg, I El Naqa, P E Kinahan and 3 more

Abstract readPractice Guideline
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Association ofMolecular imaging and radionuclide therapy · 2026
    Article
  5. Article
  6. Article
  7. Deep integration of clinical metadata with [European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Review
  9. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
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  11. Review
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  18. Review
  19. Assessing Respiratory Motion Stability of NovelDiagnostics (Basel, Switzerland) · 2026
    Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

M HattLaTIM, INSERM, UMR 1101, Univ Brest, Brest, France.
A K KrizsanScanoMed Ltd., Debrecen, Hungary.
A RahmimDepartments of Radiology and Physics, University of British Columbia, Vancouver, BC, Canada.
T J BradshawDepartment of Radiology, University of Wisconsin, Madison, WI, USA.
P F CostaDepartment of Nuclear Medicine, West German Cancer Center, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
A ForgacsScanoMed Ltd., Debrecen, Hungary.
R SeifertDepartment of Nuclear Medicine, West German Cancer Center, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany. robert.seifert@uni-muenster.de.
A ZwanenburgOncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.ORCID 0000-0002-0342-9545
I El NaqaDepartment of Machine Learning, Moffitt Cancer Center, Tampa, FL, 33626, USA.
P E KinahanImaging Research Laboratory, PET/CT Physics, Department of Radiology, UW Medical Center, University of Washington, Seattle, WA, USA.
F TixierLaTIM, INSERM, UMR 1101, Univ Brest, Brest, France.
A K JhaMcKelvey School of Engineering and Mallinckrodt Institute of Radiology, Washington University in St. Louis, Saint Louis, MO, USA.
D VisvikisLaTIM, INSERM, UMR 1101, Univ Brest, Brest, France.

Funding

Combined radiation acoustics and ultrasound imaging for real-time guidance in radiotherapyR37CA222215 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2018 to 2024
$3.5M
Optimal Decision Making in Radiotherapy Using Panomics AnalyticsR01CA233487 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2019 to 2023
$2.4M
NCI NIH HHS R01 CA233487NCI NIH HHS R37 CA222215
6 · The paper itself

Abstract

purposeThe purpose of this guideline is to provide comprehensive information on best practices for robust radiomics analyses for both hand-crafted and deep learning-based approaches.

methodsIn a cooperative effort between the EANM and SNMMI, we agreed upon current best practices and recommendations for relevant aspects of radiomics analyses, including study design, quality assurance, data collection, impact of acquisition and reconstruction, detection and segmentation, feature standardization and implementation, as well as appropriate modelling schemes, model evaluation, and interpretation. We also offer an outlook for future perspectives.

conclusionRadiomics is a very quickly evolving field of research. The present guideline focused on established findings as well as recommendations based on the state of the art. Though this guideline recognizes both hand-crafted and deep learning-based radiomics approaches, it primarily focuses on the former as this field is more mature. This guideline will be updated once more studies and results have contributed to improved consensus regarding the application of deep learning methods for radiomics. Although methodological recommendations in the present document are valid for most medical image modalities, we focus here on nuclear medicine, and specific recommendations when necessary are made for PET/CT, PET/MR, and quantitative SPECT.

Indexed as

Nuclear MedicineData ScienceHumansPhysicsPositron Emission Tomography Computed TomographyRadionuclide ImagingDeep learningMachine learningNuclear medicineRadiomicsRecommendations

Identifiers

PMID36326868
PMCPMC9816255

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.