Evidence map›Paper›PMID 36326398›Full record

ReviewTurkish journal of medical sciences2022

CHA2DS2-VASc score as a prognostic indicator in patients with atrial fibrillation undergoing coronary stenting.

Jian-Yong Zheng, Dong-Tao Li, Yi-Gang Qıu, Yi-Xiong Huang, Zheng-Ming Xu, Li Zhao, Yu Chen, Yi Cao, Yi-Da Tang, Cheng-Jun Guo and 4 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Turkish journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Jian-Yong ZhengDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Dong-Tao LiDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Yi-Gang QıuDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Yi-Xiong HuangDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Zheng-Ming XuDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Li ZhaoDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Yu ChenDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Yi CaoDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Yi-Da TangDepartment of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Cheng-Jun GuoDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhi-Min MaDepartment of Cardiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yong-Quan WuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China ; Department of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yan JıaoCatheter Lab for Cardiovascular and Neurological Intervention, Binzhou Medical University Hospital, Binzhou, Shandong Province, China.
Tian-Chang LiDepartment of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNBeijing Tongren Hospital · CNBinzhou University · CNCapital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with atrial fibrillation (AF) and coronary stenting had a poor prognosis. This study aimed to assess the accuracy of CHA2DS2-VASc score for predicting and grading adverse clinical outcomes in this population.

methodsWe reviewed the clinical data of all patients with previously documented nonvalvular AF who underwent coronary stenting between January 2010 and June 2015 in 12 hospitals of Beijing, China. The study population was divided into three groups: 1) Low CHA2DS2-VASc score, ≦ 2 points, 2) Intermediate score, 3-4 points, and 3) High score, ≧ 5 points. Major adverse cardiac/cerebrovascular events (MACCE) were defined as a composite of all-cause death, nonfatal myocardial infarction, repeat revascularization and ischemic stroke/systemic thromboembolism (IS/SE).

resultsA total of 2394 patients (men: 72.3% vs. women: 27.7%, median age: 67 years) were included, with the CHA2 DS2-VASc score of 3.6 ± 1.6. The median follow-up duration was 36.2 months. All-cause mortality increased 3 folds from the low score (4.8%) to the high score group (15.8%). The high score group had more IS/SE (7.4%) and MACCE (26.3%). The CHA2 DS2-VASc score ≧ 5 points was independently associated with all-cause death (hazard ratio [HR]: 2.303, 95% confidence interval [CI]: 1.492- 3.555), IS/SE (HR: 4.169, 95% CI: 2.216-7.845) and MACCE (HR: 1.468, 95% CI: 1.113-1.936) on multivariate Cox proportional hazards regression. The area under the receiver operating characteristic curve of the CHA2DS2-VASc score was 0.644 (95% CI: 0.624-0.663) for all-cause death, 0.647 (95% CI: 0.627-0.666) for IS/SE, and 0.592 (95% CI: 0.572-0.611) for MACCE. DISCUSSION: CHA2DS2-VASc score was a reliable prognostic indicator in patients with AF and coronary stenting.

Indexed as

Atrial FibrillationStrokeAgedFemaleHumansMalePrognosisRisk AssessmentRisk Factorsatrial fibrillationCHA2DS2-VASc scoreCoronary atherosclerotic diseasepercutaneous coronary interventionprognosis

Identifiers

PMID36326398
PMCPMC10388117
OpenAlexW4291498124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.