Evidence map›Paper›PMID 36326319›Full record

ArticleTurkish journal of medical sciences2022

Paraoxonase-1 and fetuin-A levels in children with cerebral palsy.

Özlem Unay Demirel, Özlem Güngör, Seyda İğnak Tarlığ, Meral Yüksel

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Özlem Unay DemirelDepartment of Medical Biochemistry and Bahçeşehir University Göztepe Medical Park Hospital Central Laboratory, Faculty of Medicine, Bahçeşehir University, İstanbul, Turkey.
Özlem GüngörDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bahçeşehir University, İstanbul, Turkey.
Seyda İğnak TarlığDepartment of Medical Biology, Faculty of Medicine, Bahçeşehir University, İstanbul, Turkey.
Meral YükselDepartment of Medical Laboratory Techniques, Vocational School of Health Services, Marmara University, İstanbul, Turkey.
Bahçeşehir University · TRMarmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies mostly focused on risk factors and clinical status in children with cerebral palsy (CP). Various antiinflammatory markers may help us in the early diagnosis and clinical classification of cerebral palsy patients. In this study, the relationship between antiinflammatory marker levels and clinical status in patients with CP is determined. It is the first time that Fetuin-A and Paraoxonase-1 (PON-1) are examined in children with CP.

methodsThe study is conducted on 79 children which are divided into two groups as CP and control. Gross motor function and spasticity are evaluated in addition to biochemical parameters.

resultsThere is a statistically significant difference between CP and control group in terms of PON-1 activity, high sensitive C-Reactive Protein, HDL, and total cholesterol levels. There is no statistically significant difference in Fetuin A levels between the two groups. DISCUSSION: In suspected CP patients less than 24 months of age who possess prenatal and postnatal risk factors, the determination of PON-1 activity can be considered as a biomarker to support early diagnosis.

Indexed as

Cerebral Palsyalpha-2-HS-GlycoproteinAryldialkylphosphataseChildHumansMuscle Spasticityalpha-2-HS-GlycoproteinAryldialkylphosphatasePON1 protein, humancerebral palsychildrenFetuin-Aparaoxanase-1

Identifiers

PMID36326319
PMCPMC10390159
OpenAlexW4285307181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.