ArticleJournal of bacteriology2022
Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification Systems.
Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 18 citations in OpenAlex.
- A user-friendly strategy to engineer tailored intermediate strains for overcoming combined type I and type II restriction-modification barriers inSynthetic and systems biotechnology · 2027Article
- AI-2 production inJournal of bacteriology · 2026Article
- Nicotinamide attenuates the virulence of colorectal cancer-associatedInfection and immunity · 2026Article
- Cadherin-11 serves as a novel receptor for Fusobacterium nucleatum adhesin FadA to exacerbate pulmonary inflammation.PLoS pathogens · 2026Article
- Gene Silencing by CRISPR Interference in Fusobacterium nucleatum.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Recent perspectives on precision-targeting therapy against oral biofilm.Journal of oral microbiology · 2026Review
- Methods for the Evasion of Restriction-Modification Systems During Genetic Engineering of Fusobacterium Species.Methods in molecular biology (Clifton, N.J.) · 2026Article
- A Conditional Plasmid System for Markerless Gene Deletion in Genetically Recalcitrant Fusobacterium nucleatum subsp. animalis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Conjugation-based genetic manipulation ofmBio · 2025Article
- Establishment and improvement of genetic manipulation tools forEngineering microbiology · 2025Review
- Development of a conditional plasmid for gene deletion in non-modelApplied and environmental microbiology · 2025Article
- Development of SacB-based counterselection for efficient allelic exchange inMicrobiology spectrum · 2025Article
- Transcriptome fine-mapping inmBio · 2024Article
- Article
- Use of CRISPR interference for efficient and rapid gene inactivation inApplied and environmental microbiology · 2024Article
- Spatiotemporal monitoring of a periodontal multispecies biofilm model: demonstration of prebiotic treatment responses.Applied and environmental microbiology · 2023Article
- HicA Toxin-Based Counterselection Marker for Allelic Exchange Mutations in Fusobacterium nucleatum.Applied and environmental microbiology · 2023Article
- Reexamining the role ofGut microbesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial restriction-modification (R-M) systems are a first-line immune defense against foreign DNA from viruses and other bacteria. While R-M systems are critical in maintaining genome integrity, R-M nucleases unfortunately present significant barriers to targeted genetic modification. Bacteria of the genus
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.