Evidence map›Paper›PMID 36326235›Full record

ArticleBJS open2022

Association of anaemia, co-morbidities and red blood cell transfusion according to age groups: multicentre sub-analysis of the German Patient Blood Management Network Registry.

Lea Valeska Blum, Elke Schmitt, Suma Choorapoikayil, Olaf Baumhove, Alexandra Bayer, Patrick Friederich, Jens Friedrich, Christof Geisen, Matthias Gruenewald, Martin Gutjahr and 14 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BJS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 1 country.

Lea Valeska BlumDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Elke SchmittDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Suma ChoorapoikayilDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Olaf BaumhoveDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Klinikum Westmuensterland, Bocholt, Germany.
Alexandra BayerDepartment of Anaesthesiology and Intensive Care Medicine, Agatharied Hospital, Hausham, Germany.
Patrick FriederichDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, Munich, Germany.
Jens FriedrichDepartment of Anaesthesiology and Intensive Care Medicine, Klinikum Leverkusen, Leverkusen, Germany.
Christof GeisenGerman Red Cross, Institute for Transfusion Medicine and Immunohaematology, German Red Cross Baden-Wuertemberg-Hessen, Goethe University Frankfurt, Frankfurt am Main, Germany.
Matthias GruenewaldDepartment of Anaesthesiology and Operative Intensive Care Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.
Martin GutjahrDepartment of Anaesthesiology, Marienhaus, Ottweiler, Germany.
Eva HerrmannDepartment of Medicine, Institute of Biostatistics and Mathematical Modelling, Goethe University, Frankfurt, Germany.ORCID 0000-0002-0662-6675
Markus MüllerGerman Red Cross, Institute for Transfusion Medicine and Immunohaematology, German Red Cross Baden-Wuertemberg-Hessen, Goethe University Frankfurt, Frankfurt am Main, Germany.
Diana NaritaInstitute for Laboratory Diagnostics and Transfusion Medicine, Donauisarklinikum, Deggendorf, Germany.
Ansgar RaadtsDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Jena, Jena, Germany.
Klaus SchwendnerDepartment of Anaesthesiology and Operative Intensive Care Medicine, Diakonie Hospital Martha-Maria, Nuremberg, Germany.
Erhard SeifriedGerman Red Cross, Institute for Transfusion Medicine and Immunohaematology, German Red Cross Baden-Wuertemberg-Hessen, Goethe University Frankfurt, Frankfurt am Main, Germany.
Patrick StarkDepartment of Visceral and Vascular Surgery, Klinikum Mittelmosel, Zell, Germany.
Josef ThomaDepartment of Anaesthesiology and Operative Intensive Care Medicine, Ortenauklinikum, Gengenbach, Germany.
Henry WeigtDepartment of Anaesthesiology, SLK-Kliniken, Heilbronn, Germany.
Christoph WiesenackDepartment of Anaesthesiology, Evangelisches Diakoniekrankenhaus Freiburg, Freiburg, Germany.
Andrea Ulrike SteinbickerDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Kai ZacharowskiDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Patrick MeybohmDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
German PBM Network Collaborators
Goethe University Frankfurt · DEOrtenau Klinikum · DEDeggendorf Institute of Technology · DEEvangelisches Diakoniekrankenhaus · DEKlinikum Leverkusen · DEKrankenhaus Agatharied · DEUniversity Hospital Schleswig-Holstein · DEJena University Hospital · DEMartha-Maria Hospital · DESLK-Kliniken Heilbronn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood transfusions are common medical procedures and every age group requires detailed insights and treatment bundles. The aim of this study was to examine the association of anaemia, co-morbidities, complications, in-hospital mortality, and transfusion according to age groups to identify patient groups who are particularly at risk when undergoing surgery.

methodsData from 21 Hospitals of the Patient Blood Management Network Registry were analysed. Patients were divided into age subgroups. The incidence of preoperative anaemia, co-morbidities, surgical disciplines, hospital length of stay, complications, in-hospital mortality rate, and transfusions were analysed by descriptive and multivariate regression analysis.

resultsA total of 1 117 919 patients aged 18-108 years were included. With increasing age, the number of co-morbidities and incidence of preoperative anaemia increased. Complications, hospital length of stay, and in-hospital mortality increased with age and were higher in patients with preoperative anaemia. The mean number of transfused red blood cells (RBCs) peaked, whereas the transfusion rate increased continuously. Multivariate regression analysis showed that increasing age, co-morbidities, and preoperative anaemia were independent risk factors for complications, longer hospital length of stay, in-hospital mortality, and the need for RBC transfusion.

conclusionIncreasing age, co-morbidities, and preoperative anaemia are independent risk factors for complications, longer hospital length of stay, in-hospital mortality, and the need for RBC transfusion. Anaemia diagnosis and treatment should be established in all patients.

Indexed as

AnemiaErythrocyte TransfusionBlood TransfusionHumansIncidenceRegistries

Identifiers

PMID36326235
PMCPMC9631974
OpenAlexW4308482026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.