ReviewJournal of the American Heart Association2022
Intravascular Imaging for Guiding In-Stent Restenosis and Stent Thrombosis Therapy.
Review in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06039059 (Influence of Risk Factors Such as Serum Cholesterol Level on ISR and Nonintervened Coronary Lesions), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Risk Factors Such as Serum Cholesterol Level on ISR and Nonintervened Coronary Lesions
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Drug-coated balloons in coronary in-stent restenosis: a systematic review and meta-analysis comparing sirolimus and biolimus with paclitaxel platforms.Cardiovascular intervention and therapeutics · 2026Pooled it
- Beyond Angiography: Integrating Advanced Diagnostic Modalities in Coronary Stent Restenosis-a Systematic Review.International journal of medical sciences · 2026Pooled it
- Risk prediction model for in-stent restenosis following PCI: a systematic review.Frontiers in cardiovascular medicine · 2024Pooled it
- Single-Cell Transcriptomics Reveals the Immune Pathogenesis of Isolated Coronary Arteritis Presenting as Refractory In-Stent Restenosis.JACC. Basic to translational science · 2026Article
- A Study of Coronary Stent Thrombosis Growth.Bioengineering (Basel, Switzerland) · 2026Article
- Impact of IVUS Guidance on Clinical and Procedural Outcomes in Intracoronary Brachytherapy.JACC. Advances · 2026Article
- Role of Intracoronary Imaging in Percutaneous Coronary Intervention for In-Stent Restenosis: A Prospective Observational Study.Cardiology research · 2026Article
- Glucocorticoid Therapy for Recurrent In-Stent Restenosis: A Prospective Explorative Case Series.JACC. Case reports · 2026Article
- Determinants of In-Stent Restenosis in ST-Elevation Myocardial Infarction: Insights from a Single-Center Retrospective Analysis.Medicina (Kaunas, Lithuania) · 2026Observational
- Association between systemic immune-inflammation index and systemic inflammation response index and in-stent restenosis in patients with hypertension complicated by coronary heart disease.BMC cardiovascular disorders · 2026Article
- In-Stent Restenosis Pathophysiology and Risk Factors: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2026Review
- Self-powered in-stent restenosis diagnosis via magnetoelastic stents.Nature cardiovascular research · 2026Article
- Excimer Laser Coronary Atherectomy: Current Evidence, Clinical Applications, and Future Directions.Journal of clinical medicine · 2026Review
- Ultrathin-strut drug-eluting stents are associated with lower revascularization rates than drug-coated balloons in non-focal in-stent restenosis.Frontiers in cardiovascular medicine · 2026Article
- Threshold effect of systemic immune-response index on in-stent neoatherosclerosis among patients with drug-eluting stent restenosis.European journal of medical research · 2025Article
- Article
- The Rise of Optical Coherent Tomography in Intracoronary Imaging: An Overview of Current Technology, Limitations, and Future Perspectives.Reviews in cardiovascular medicine · 2025Review
- Review of Optical Imaging in Coronary Artery Disease Diagnosis.Journal of cardiovascular development and disease · 2025Review
- Molecular mechanisms of endothelial-mesenchymal transition and its pathophysiological feature in cerebrovascular disease.Cell & bioscience · 2025Review
- From Mechanisms to Management: Tackling In-Stent Restenosis in the Drug-Eluting Stent Era.Current cardiology reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
Abstract
Advances in stent technology and the design of endovascular devices with thinner struts, anti-inflammatory and antithrombotic polymers, and better drug kinetics have enhanced the safety and efficacy of the second-generation drug-eluting stents and broadened their use in the therapy of high-risk patients and complex anatomies. However, despite these developments, in-stent restenosis and stent thrombosis remain the Achilles' heel of percutaneous coronary intervention, with their cumulative incidence reaching up to 10% at 5 years following percutaneous coronary intervention. The treatment of stent failure poses challenges and is associated with a worse prognosis than conventional percutaneous coronary intervention. Several studies have recently highlighted the value of intravascular imaging in identifying causes of stent failure, underscored its role in treatment planning, and registries have shown that its use may be associated with better clinical outcomes. The present review aims to summarize the evidence in the field; it discusses the value of intravascular imaging in identifying the mechanisms of in-stent restenosis and stent thrombosis in assessing the morphological characteristics of neointima tissue that appears to determine long-term outcomes in evaluating procedural results, and presents the findings of studies supporting its value in guiding therapy in stent failure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.