Evidence map›Paper›PMID 36325887›Full record

ArticleDepression and anxiety2022

Real-time assessment of positive and negative affective fluctuations and mood lability in a transdiagnostic sample of youth.

Reut Naim, Shannon Shaughnessy, Ashley Smith, Sarah L Karalunas, Katharina Kircanski, Melissa A Brotman

Open access · hybridAbstract read
In one paragraph

Article in Depression and anxiety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Momentary Dynamics Implicate Emotional Features in the ADHD Phenotype.Research on child and adolescent psychopathology · 2024
    Article
  9. Sleepless nights, sour moods: daily sleep-irritability links in a pediatric clinical sample.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Reut NaimEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
Shannon ShaughnessyEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
Ashley SmithEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
Sarah L KaralunasDepartment of Psychological Sciences, Purdue University, West Lafayette, Indiana, USA.
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health, Bethesda, Maryland, USA.
National Institute of Mental Health · USPurdue University West Lafayette · US

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
The Pathophysiology and Treatment Of Children With Severe Mood DysregulationZIAMH002786 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2023
$34.0M
The Phenomenology And Neurophysiology Of Juvenile Bipolar DisorderZIAMH002778 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2017
$10.8M
Intramural NIH HHS ZIA MH002778Intramural NIH HHS ZIA MH002781Intramural NIH HHS ZIA MH002786
6 · The paper itself

Abstract

backgroundEmotional lability, defined as rapid and/or intense affect fluctuations, is associated with pediatric psychopathology. Although numerous studies have examined labile mood in clinical groups, few studies have used real-time assessments in a well-characterized transdiagnostic sample, and no prior study has included participants with disruptive mood dysregulation disorder (DMDD). The present study leverages ecological momentary assessment (EMA) to assess emotional lability in a transdiagnostic pediatric sample.

methodsOne hundred thirty participants ages 8-18 with primary diagnoses of DMDD, attention-deficit/hyperactivity disorder (ADHD), an anxiety disorder (ANX), or healthy volunteers completed a previously validated 1-week EMA protocol. Clinicians determined diagnoses based on semi-structured interviews and assessed levels of functional impairment. Participants reported momentary affective states and mood change. Composite scores of fluctuations in positive and negative affect were generated. Affect fluctuations were compared between diagnostic groups and tested for their association with functional impairment.

resultsDiagnostic groups differed in levels of negative and positive emotional lability. DMDD patients demonstrated the highest level of labile mood compared with other groups. Emotional lability was associated with global impairment in the whole sample.

conclusionsBoth positive and negative emotional lability is salient in pediatric psychopathology and is associated with functional impairment, particularly in DMDD youth.

Indexed as

Attention Deficit Disorder with HyperactivityMood DisordersAdolescentAffective SymptomsAttention Deficit and Disruptive Behavior DisordersChildHumansPsychopathologyanxietyattention-deficit/hyperactivity disorderdisruptive mood dysregulation disorderecological momentary assessmentemotional lability

Identifiers

PMID36325887
PMCPMC9729410
OpenAlexW4308059432

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.