Evidence map›Paper›PMID 36325471›Full record

ArticleFrontiers in cellular and infection microbiology2022

Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for

Angelica F Tan, Sitti Saimah Binti Sakam, Giri S Rajahram, Timothy William, Mohammad Faruq Abd Rachman Isnadi, Sylvia Daim, Bridget E Barber, Steven Kho, Colin J Sutherland, Nicholas M Anstey and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Evaluation ofiScience · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Improved limit of detection for zoonoticmedRxiv : the preprint server for health sciences · 2024
    Article
  14. Article
  15. Clarifying the terms parasitemia, parasite density, and parasite count.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2023
    Article
  16. Lactate Dehydrogenase Gene Family inAnimals : an open access journal from MDPI · 2023
    Article
  17. Tropical medicine and infectious disease · 2023
    Review
  18. Article
  19. PredictingFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Angelica F TanGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, N T, Australia.
Sitti Saimah Binti SakamInfectious Diseases Society Kota Kinabalu Sabah - Menzies School of Health Research Clinical Research Unit, Kota Kinabalu, Sabah, Malaysia.
Giri S RajahramInfectious Diseases Society Kota Kinabalu Sabah - Menzies School of Health Research Clinical Research Unit, Kota Kinabalu, Sabah, Malaysia.
Timothy WilliamInfectious Diseases Society Kota Kinabalu Sabah - Menzies School of Health Research Clinical Research Unit, Kota Kinabalu, Sabah, Malaysia.
Mohammad Faruq Abd Rachman IsnadiFaculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
Sylvia DaimFaculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
Bridget E BarberGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, N T, Australia.
Steven KhoGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, N T, Australia.
Colin J SutherlandFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Nicholas M AnsteyGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, N T, Australia.
Seda YerlikayaMalaria and Fever, Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Donelly A van SchalkwykFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Matthew J GriggGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, N T, Australia.
Charles Darwin University · AULondon School of Hygiene & Tropical Medicine · GBMenzies School of Health Research · AUMinistry of Health · MYUniversiti of Malaysia Sabah · MYFoundation for Innovative New Diagnostics · CHQIMR Berghofer Medical Research Institute · AU

Funding

Emerging zoonotic malaria in Malaysia: strengthening surveillance and evaluating population genetic structure to improve regional risk prediction toolsR01AI160457 · NIAID · INFECTIOUS DISEASE SOCIETY KOTA KINABALU · PI RAJAHRAM, GIRI · 2021 to 2025
$674k
NIAID NIH HHS R01 AI160457
6 · The paper itself

Abstract

Background: Methods: Ten RDTs were evaluated: nine to detect clinical Results: Samples were collected prior to antimalarial treatment from 127 patients with microscopy-positive PCR-confirmed Conclusion: Selected RDTs demonstrate sufficient performance for detection of major human malaria species including

Indexed as

AntimalarialsMalariaMalaria, FalciparumMalaria, VivaxParasitesPlasmodium knowlesiAnimalsAntigens, ProtozoanDiagnostic Tests, RoutineHumansLimit of DetectionL-Lactate DehydrogenasePlasmodium falciparumPlasmodium vivaxProtozoan ProteinsSensitivity and SpecificityAntigens, ProtozoanAntimalarialsL-Lactate DehydrogenaseProtozoan Proteinsdiagnostic performancemalariaMalaysiaparasite lactate dehydrogenasePlasmodium knowlesipoint-of-carerapid diagnostic test

Identifiers

PMID36325471
PMCPMC9618705
OpenAlexW4306382375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.