Evidence map›Paper›PMID 36325392›Full record

SynthesisFrontiers in medicine2022

The add-on effect of Shufeng Jiedu capsule for treating COVID-19: A systematic review and meta-analysis.

Xiaodi Sheng, Chao Chen, Guowang Jiang, Zhaochen Ji, Zehui Guo, Haiyin Hu, Hui Wang, Jingbo Zhai, Dong Zhang, Junhua Zhang and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. In silico andFrontiers in cellular and infection microbiology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaodi ShengEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Chao ChenFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Guowang JiangTianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhaochen JiEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zehui GuoTianjin University of Traditional Chinese Medicine, Tianjin, China.
Haiyin HuEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Hui WangEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jingbo ZhaiEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Dong ZhangEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Junhua ZhangEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Liping GuoTianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Shufeng Jiedu capsule (SFJD) is a commonly used Chinese patent medicine in China. Some studies have reported that SFJD has therapeutic effects in patients diagnosed with COVID-19. This systematic review aimed to critically evaluate the efficacy and safety of SFJD combined with western medicine (WM) for treating COVID-19. Methods: A literature search by using WHO COVID-19 database, PubMed, Embase, Cochrane Library, the Web of Science, CKNI, Wanfang, VIP, SinoMed, and clinical trial registries was conducted, up to 1 August 2022. Randomized controlled trials (RCTs), non-RCTs, cohort studies and case series of SFJD combined with WM for COVID-19 were included. Literature screening, data extraction, and quality assessment were performed independently by two reviewers in line with the same criteria. We used the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) to assess the certainty of evidence. Meta-analyses were performed with Revman 5.3 if possible. The descriptive analysis was conducted when the studies could not be meta-analyzed. Results: Totally 10 studies with 1,083 patients were included. Their methodological quality were moderate. The results demonstrated that compared to WM group, SFJD + WM group remarkably increased the nucleic acid negative conversion rate ( Conclusion: SFJD combined with WM seems more effective than WM alone for the treatment of COVID-19. However, more well-designed RCTs still are warranted. Systematic review registration: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD42022306307].

Indexed as

COVID-19meta-analysisShufeng Jiedu capsulesystematic reviewtraditional Chinese medicine

Identifiers

PMID36325392
PMCPMC9620801

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.