Evidence map›Paper›PMID 36325382›Full record

ArticleFrontiers in medicine2022

Epidemiology, management, and outcome of infection, sepsis, and septic shock in a German emergency department (EpiSEP study).

Nicole Wolfertz, Lennert Böhm, Verena Keitel, Oliver Hannappel, Philipp Kümpers, Michael Bernhard, Mark Michael

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Detection of pathogenic microorganisms using metagenomic next generation sequencing for patients with suspected infection presenting in the emergency department.European journal of emergency medicine : official journal of the European Society for Emergency Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicole WolfertzEmergency Department, Medical Faculty, University Hospital of Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Lennert BöhmEmergency Department, Medical Faculty, University Hospital of Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Verena KeitelClinic for Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, University Hospital of Düsseldorf, University of Magdeburg, Magdeburg, Germany.
Oliver HannappelInformations-, Kommunikations- und Medizintechnik (IKMT), University Hospital of Düsseldorf, Düsseldorf, Germany.
Philipp KümpersDivision of General Internal and Emergency Medicine, Nephrology, Hypertension and Rheumatology, Department of Medicine D, Münster University Hospital, Münster, Germany.
Michael BernhardEmergency Department, Medical Faculty, University Hospital of Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Mark MichaelEmergency Department, Medical Faculty, University Hospital of Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The adjacent conditions infection, sepsis, and septic shock are among the most common causes of treatment in the emergency department (ED). Most available data come from intensive care units (ICU) and include nosocomial infections acquired during hospitalization. Epidemiological data from German EDs are not yet available, although the ED is one of the first points of contact for patients. The aim of this study was to investigate the epidemiology, causes, diagnosis, mortality, and treatment of patients with infections in the ED. Materials and methods: In this retrospective, single-center observational study, routinely collected data from the patient data management system and from the hospital information system were analyzed. All adult patients who presented to the ED in connection with an infection during the study period from 01/01 to 28/02/2019 were included. Exclusion criteria were age ≤ 17 years and incomplete records. Three groups (I. Infection, II. Sepsis, and III. Septic shock) were defined according to SEPSIS-3 definitions. Results: During the study period, a total of 6,607 patients were treated in the ED. Of these patients, 19.3% ( Conclusion: This study is the first to show the incidence, management, and outcome of patients classified as infection, sepsis, and septic shock in a German ED. The findings of our real-world data are important for quality management and enable the optimization of treatment pathways for patients with infectious diseases.

Indexed as

emergency departmentepidemiologyinfectionsepsisseptic shock

Identifiers

PMID36325382
PMCPMC9618593

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.