Evidence map›Paper›PMID 36325322›Full record

ReviewFrontiers in immunology2022

Progress in the application of body fluid and tissue level mRNAs-non-coding RNAs for the early diagnosis and prognostic evaluation of systemic lupus erythematosus.

Jiabin Liang, Fangmei Xie, Jie Feng, Chen Huang, Jian Shen, Zeping Han, Wenfeng Luo, Jinhua He, Hanwei Chen

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiabin LiangCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Fangmei XieCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Jie FengRadiology Department of Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Chen HuangCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Jian ShenCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Zeping HanCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Wenfeng LuoCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Jinhua HeCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.
Hanwei ChenCentral Laboratory of Guangzhou Panyu Central Hospital, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis and differential classification of systemic lupus erythematosus (SLE) is difficult, especially in patients with early-onset SLE who are susceptible to systemic multi-organ damage and serious complications and have difficulties in individualized treatment. At present, diagnosis is based mainly on clinical manifestations and the detection of serological antinuclear antibodies. The pathogenesis of SLE involves multiple factors, is clinically heterogeneous, and lacks specific biomarkers. Therefore, it is necessary to identify new biomarkers for the diagnosis and subtype classification of SLE. Non-coding RNAs (ncRNAs) are composed of microRNAs, long non-coding RNAs, small nucleolar RNAs, circular RNAs, and transfer RNAs. They play an important role in the occurrence and development of diseases and are used widely in the early diagnosis and prognosis of autoimmune diseases. In this review, we focus on the research progress in the diagnosis and prognostic assessment of SLE using humoral to tissue level ncRNAs.

Indexed as

Body FluidsLupus Erythematosus, SystemicBiomarkersEarly DiagnosisHumansPrognosisRNA, MessengerRNA, UntranslatedBiomarkersRNA, MessengerRNA, UntranslatedbiomarkercircRNAdiagnosislncRNAmicroRNAmRNAsnoRNAsystemic lupus erythematosus

Identifiers

PMID36325322
PMCPMC9618628

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.