Evidence map›Paper›PMID 36325318›Full record

ReviewFrontiers in immunology2022

Anti-SARS-CoV-2 vaccination in people with multiple sclerosis: Lessons learnt a year in.

Maura Pugliatti, Hans-Peter Hartung, Celia Oreja-Guevara, Carlo Pozzilli, Laura Airas, Mona Alkhawajah, Nikolaos Grigoriadis, Melinda Magyari, Bart Van Wijmeersch, Magd Zakaria and 4 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Is there still hesitancy towards SARS-CoV-2 vaccination among people with neurological disease- a survey of the NeuroCOVID-19 task force of the European Academy of Neurology.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maura PugliattiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Hans-Peter HartungDepartment of Neurology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Celia Oreja-GuevaraDepartment of Neurology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Carlo PozzilliMultiple Sclerosis Center, S. Andrea Hospital, Department of Human Neuroscience, University Sapienza, Rome, Italy.
Laura AirasDivision of Clinical Neurosciences, University of Turku, Turku, Finland.
Mona AlkhawajahSection of Neurology, Neurosciences Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Nikolaos GrigoriadisLaboratory of Experimental Neurology and Neuroimmunology, Second Department of Neurology, American Hellenic Educational Progressive Association (AHEPA) University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Melinda MagyariDanish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Bart Van WijmeerschUniversitair Multiple Sclerosis (MS) Centrum, Hasselt-Pelt, Belgium.
Magd ZakariaDepartment of Neurology, Ain Shams University, Cairo, Egypt.
Ralf LinkerClinic and Polyclinic for Neurology, Universitätsklinikum Regensburg, Regensburg, Germany.
Andrew ChanDepartment of Neurology, Inselspital Bern, Bern University Hospital, University of Bern, Bern, Switzerland.
Patrick VermerschUniversity of Lille, Inserm U1172 LilNCog, CHU Lille, FHU Precise, Lille, France.
Thomas BergerDepartment of Neurology, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been over a year since people with multiple sclerosis (pwMS) have been receiving vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With a negligible number of cases in which vaccination led to a relapse or new onset MS, experts around the world agree that the potential consequences of COVID-19 in pwMS by far outweigh the risks of vaccination. This article reviews the currently available types of anti-SARS-CoV-2 vaccines and the immune responses they elicit in pwMS treated with different DMTs. Findings to date highlight the importance of vaccine timing in relation to DMT dosing to maximize protection, and of encouraging pwMS to get booster doses when offered.

Indexed as

COVID-19Multiple SclerosisCOVID-19 VaccinesHumansSARS-CoV-2VaccinationCOVID-19 Vaccinesadverse eventsCOVID-19disease modifying therapiesimmune responsemultiple sclerosisSARS-CoV-2vaccines

Identifiers

PMID36325318
PMCPMC9620960

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.