Evidence map›Paper›PMID 36325001›Full record

ReviewClinical kidney journal2022

Frailty in kidney transplantation: a review on its evaluation, variation and long-term impact.

Carlo Alfieri, Silvia Malvica, Matteo Cesari, Simone Vettoretti, Matteo Benedetti, Elisa Cicero, Roberta Miglio, Lara Caldiroli, Alessandro Perna, Angela Cervesato and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07181096 (Study of Frailty Among Renal Transplant Recipients, Its Relation to Chronic Renal Allograft Dysfunction), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07181096 narecruitingnot on this mapstarted 2025, after this paper: background citation

Study of Frailty Among Renal Transplant Recipients, Its Relation to Chronic Renal Allograft Dysfunction

TypeinterventionalSponsorAlexandria UniversityRan2025 to 2026Enrolled80ConditionsFrailty, Renal TransplantArmsassessment of frailty
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  10. Article
  11. Article
  12. Frailty status improvement after kidney transplantation.Irish journal of medical science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlo AlfieriDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.ORCID https://orcid.org/0000-0003-3860-5219
Silvia MalvicaDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Matteo CesariDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Simone VettorettiDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Matteo BenedettiDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Elisa CiceroDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Roberta MiglioDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Lara CaldiroliDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.
Alessandro PernaDepartment of Translational Medical Sciences, University of Campania 'L. Vanvitelli', Naples, Italy.
Angela CervesatoDepartment of Translational Medical Sciences, University of Campania 'L. Vanvitelli', Naples, Italy.
Giuseppe CastellanoDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The problem of frailty in kidney transplantation is an increasingly discussed topic in the transplant field, partially also generated by the multiple comorbidities by which these patients are affected. The criteria currently used to establish the presence and degree of frailty can be rapidly assessed in clinical practice, even in patients with chronic kidney disease (CKD). The main objectives of this work are: (i) to describe the method of evaluation and the impact that frailty has in patients affected by CKD, (ii) to explore how frailty should be studied in the pre-transplant evaluation, (iii) how frailty changes after a transplant and (iv) the impact frailty has over the long term on the survival of renal transplant patients.

Indexed as

chronic kidney diseasefrailtygraft survivalrenal transplantation

Identifiers

PMID36325001
PMCPMC9613431

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.