ArticleSurgical neurology international2022
Dorsal vertebral body tumor and non-compressive quadriparesis - A rare case report of a phosphaturic mesenchymal tumor.
Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Phosphaturic mesenchymal tumors cause renal phosphate wasting leading to hypophosphatemia manifesting as bone pain and fractures. About 95% of these tumors involve the extremities and the appendicular skeleton, with spinal tumors being exceedingly rare. We describe a case of non-compressive quadriparesis, caused by a thoracic vertebral body phosphaturic mesenchymal tumor (PMT). Case Description: A 34-year-old gentleman presented with a 3-year history of gradually progressive quadriparesis, predominantly involving proximal muscles. Magnetic resonance imaging neither showed evidence of compressive lesions nor myelopathy. On routine biochemistry, he was found to have hypophosphatemia and phosphaturia, with serum phosphorus levels of 1.84 mg/dl, and fractional excretion of phosphorus >5%. A DOTATOC positron emission tomography scan suggested the possibility of a PMT in the D10 vertebral body with a corresponding hyperdense/sclerotic focus on non-contrast computed tomography. After instituting phosphate replacement therapy and complete surgical excision of the hyperdense focus, he made a full neurological recovery. His phosphate levels normalized without the need for supplements. Histopathological examination showed spindle cells with positive staining for Vimentin, a mesenchymal cell marker. At 5 years of follow-up, the patient continues to be asymptomatic with a full return to normal function and no residual weakness. Conclusion: PMTs involving the spine are a rare reversible cause of non-compressive quadriparesis. Early diagnosis and excision of the lesion correct the hypophosphatemia and result in complete neurological recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.