Evidence map›Paper›PMID 36324873›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2022

Topology of pain networks in patients with temporomandibular disorder and pain-free controls with and without concurrent experimental pain: A pilot study.

Jeremy L Smith, Jason W Allen, Candace C Fleischer, Daniel E Harper

Abstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeremy L SmithDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Jason W AllenDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Candace C FleischerDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Daniel E HarperDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States.

Funding

Mechanistic Characterization of Pain in Temporomandibular Disorders: Does Pain Centralization Influence Responsiveness to Peripherally Targeted Treatments?R00DE026810 · NIDCR · EMORY UNIVERSITY · PI HARPER, DANIEL ELLIOTT · 2020 to 2022
$739k
Mechanistic Characterization of Pain in Temporomandibular Disorders: Does Pain Centralization Influence Responsiveness to Peripherally Targeted Treatments?K99DE026810 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARPER, DANIEL ELLIOTT · 2017 to 2018
$236k
NIDCR NIH HHS K99 DE026810NIDCR NIH HHS R00 DE026810
6 · The paper itself

Abstract

Temporomandibular disorders (TMD) involve chronic pain in the masticatory muscles and jaw joints, but the mechanisms underlying the pain are heterogenous and vary across individuals. In some cases, structural, functional, and metabolic changes in the brain may underlie the condition. In the present study, we evaluated the functional connectivity between 86 regions of interest (ROIs), which were chosen based on previously reported neuroimaging studies of pain and differences in brain morphology identified in an initial surface-based morphometry analysis. Our main objectives were to investigate the topology of the network formed by these ROIs and how it differs between individuals with TMD and chronic pain (

Indexed as

chronic paingraph theoryquantitative sensory testing (QST)resting state—fMRItemporomandibular disorder (TMD)

Identifiers

PMID36324873
PMCPMC9619074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.