ArticleFrontiers in cardiovascular medicine2022
Influence of hypertension duration and blood pressure levels on cardiovascular disease and all-cause mortality: A large prospective cohort study.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Effect of Hypertension Duration on the Associations Between Intensive Blood Pressure Control and Cardiac, Vascular, and Kidney Organ Damage.Journal of the American Heart Association · 2026Trial
- Weight Trajectory in Young People Undergoing Sleeve Gastrectomy: Does Age Make a Difference? A Children's Obesity Surgery Multi-Institutional Collaborative (COSMIC) Analysis.Obesity surgery · 2026Observational
- Article
- Interrelationships Between Key Cardiovascular Risk Factors, Chronic Kidney Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease.Current cardiology reports · 2026Review
- Retinal Dysfunction in Hypertensive Patients with Atherosclerotic Plaque Detected by Carotid Doppler Ultrasound: An Optical Coherence Tomography Angiography Assessment.Life (Basel, Switzerland) · 2026Article
- Joint associations between exercising and classical cardiometabolic risk factors with all-cause, premature and cardiovascular mortality: a prospective cohort study among Mexican adults.Frontiers in endocrinology · 2026Article
- Comorbidity patterns and mortality in HFpEF: A retrospective longitudinal cohort study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Prevalence and associated factors of comorbidities among hypertensive patients in Northwest Ethiopia, 2024.BMC cardiovascular disorders · 2025Article
- Prognostic impact of the timing of antihypertensive medication initiation for hypertension detected at health screening on primary prevention of adverse cardiovascular events: Age-stratified real-world data analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Observational
- Posttraumatic stress disorder and hypertension in older adult Vietnam Era male and female veterans.Journal of traumatic stress · 2025Article
- Quantifying the association of Life's Crucial 9 with cardiovascular diseases among elderly hypertensive patients managed in primary care settings.Population health metrics · 2025Article
- Data-driven identification of key predictors of uncontrolled hypertension: A cross-sectional study.PloS one · 2025Article
- Predicting new-onset stroke with machine learning: development of a model integrating traditional Chinese and western medicine.Frontiers in pharmacology · 2025Article
- Sex Differences in the Impact of BMI on Length of Hospital Stay in Hypertensive Patients Admitted to a Cardiology Department: A Retrospective Cohort Study.Vascular health and risk management · 2024Article
- A nomogram based on endothelial function and conventional risk factors predicts coronary artery disease in hypertensives.BMC cardiovascular disorders · 2023Article
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5 authors.
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Abstract
Background and objects: A longer duration of hypertension (HTN) has been suggested to be associated with a greater risk of cardiovascular disease (CVD). Whether such an association is similar for mortality risk, and whether HTN duration is associated with CVD/mortality beyond blood pressure (BP) control levels are yet to be assessed. We aimed to examine the associations of HTN duration and the combination of HTN duration and systolic blood pressure (SBP)/diastolic blood pressure (DBP) with risks of CVD and all-cause mortality. Methods: We used data on ∼450,000 UK residents. Participants were categorized by HTN status and HTN duration. The primary outcome was a composite of non-fatal myocardial infarction, non-fatal stroke and CVD death. We also explored the results for the above-mentioned CVD outcomes separately. All-cause mortality was also used as a secondary outcome. The age at HTN diagnosis was obtained by self-report. HTN duration was calculated as baseline age minus age at diagnosis. Results: Among all participants, compared with non-hypertensive participants, those with a longer HTN duration had increased risks of CVD and all-cause mortality. These associations persisted among hypertensive patients. Specifically, compared with patients with HTN durations of < 5 y, patients with a HTN duration of 5 to < 10 y, 10 to < 15 y, and ≥ 15 y had adjusted HRs (95% CI) of 1.09 (1.03, 1.17), 1.21 (1.13, 1.31), and 1.38 (1.29, 1.48) for composite CVD ( Conclusion: A longer HTN duration was associated with increased risks of CVD and overall death in a linear fashion, and these associations were independent of BP control levels.
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