ArticleBiological psychiatry global open science2022
Controllability of Structural Brain Networks and the Waxing and Waning of Negative Affect in Daily Life.
Article in Biological psychiatry global open science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed.
- Psychological distance intervention reminders reduce alcohol consumption frequency in daily life.Scientific reports · 2023Trial
- Mindful attention promotes control of brain network dynamics for self-regulation and discontinues the past from the present.Proceedings of the National Academy of Sciences of the United States of America · 2023Trial
- Understanding Brain Functional Dynamics Through Neural Koopman Operator With Control Mechanism.IEEE transactions on medical imaging · 2025Article
- Explore brain-inspired machine intelligence for connecting dots on graphs through holographic blueprint of oscillatory synchronization.Nature communications · 2025Article
- Neural responses to peers moderate conversation-drinking associations in daily life.Scientific reports · 2025Article
- Topological Biomarkers of Alzheimer's Disease from Functional Brain Network Analysis.Current Alzheimer research · 2025Article
- A framework for optimal control of oscillations and synchrony applied to non-linear models of neural population dynamics.Frontiers in computational neuroscience · 2024Article
- Open Hardware Implementation of Real-Time Phase and Amplitude Estimation for Neurophysiologic Signals.Bioengineering (Basel, Switzerland) · 2023Article
- Dense Sampling Approaches for Psychiatry Research: Combining Scanners and Smartphones.Biological psychiatry · 2023Review
- Structure-function models of temporal, spatial, and spectral characteristics of non-invasive whole brain functional imaging.Frontiers in neuroscience · 2022Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Background: The waxing and waning of negative affect in daily life is normative, reflecting an adaptive capacity to respond flexibly to changing circumstances. However, understanding of the brain structure correlates of affective variability in naturalistic settings has been limited. Using network control theory, we examine facets of brain structure that may enable negative affect variability in daily life. Methods: We used diffusion-weighted imaging data from 95 young adults (age [in years]: mean = 20.19, SD = 1.80; 56 women) to construct structural connectivity networks that map white matter fiber connections between 200 cortical and 14 subcortical regions. We applied network control theory to these structural networks to estimate the degree to which each brain region's pattern of structural connectivity facilitates the spread of activity to other brain systems. We examined how the average controllability of functional brain systems relates to negative affect variability, computed by taking the standard deviation of negative affect self-reports collected via smartphone-based experience sampling twice per day over 28 days as participants went about their daily lives. Results: We found that high average controllability of the cingulo-insular system is associated with increased negative affect variability. We also found that greater negative affect variability is related to the presence of more depressive symptoms, yet average controllability of the cingulo-insular system was not associated with depressive symptoms. Conclusions: Our results highlight the role that brain structure plays in affective dynamics as observed in the context of daily life, suggesting that average controllability of the cingulo-insular system promotes normative negative affect variability.
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