ArticleFrontiers in public health2022
Prevalence, maternal characteristics, and birth outcomes of preeclampsia: A cross-sectional study in a single tertiary healthcare center in greater Kuala Lumpur Malaysia.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis.Frontiers in reproductive health · 2025Pooled it
- The association between ultra-processed food and common pregnancy adverse outcomes: a dose-response systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Tracking Preeclampsia: The Role of Cerebral Biomarkers-A Narrative Review.International journal of molecular sciences · 2026Review
- Preeclampsia among Omani women: prevalence and associated risk factors.Frontiers in global women's health · 2026Article
- Complications in hospitalized neonates born to mothers with HDP subtypes: a retrospective cohort study and mediation analysis.BMC pregnancy and childbirth · 2025Article
- Expectant Management of Severe Preeclampsia in Advanced Maternal Age With Multiple Risk Factors: A Case Report.Cureus · 2025Article
- Maternal physical and social characteristics that influence the occurrence of preeclampsia/eclampsia and hemorrhage in Eastern Region of Ghana. A prospective cohort study.SAGE open medicine · 2025Article
- FOXP2 overexpression upregulates LAMA4 expression and thereby alleviates preeclampsia by regulating trophoblast behavior.Communications biology · 2024Article
- Prevalence of hypertension in pregnancy and its associated sociodemographic factors among mothers aged 15-49 years old in Malaysia.Archives of public health = Archives belges de sante publique · 2024Article
- Urinary protein and coagulation-fibrinolysis indicators in preeclampsia: Expression and significance.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Vitamin D Deficiency and Its Association With Vitamin D Receptor Gene Variants Among Malaysian Women With Hypertensive Disorders in Pregnancy: Protocol for a Nutrigenomics Study.JMIR research protocols · 2024Article
- Establishing a trigger tool based on global trigger tools to identify adverse drug events in obstetric inpatients in China.BMC health services research · 2024Review
- Prevalence and determinants of adverse perinatal outcomes of preeclampsia with severe features at two selected public hospitals in Addis Ababa, Ethiopia.Frontiers in pediatrics · 2024Article
- Association of Gestational Hypertension with Sociodemographic and Anthropometric Factors, Perinatal Outcomes, Breastfeeding Practices, and Mediterranean Diet Adherence: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2023Article
- Pre-eclampsia among Pregnant Women Admitted to the Department of Obstetrics and Gynaecology of a Tertiary Care Centre.JNMA; journal of the Nepal Medical Association · 2023Article
- Maternal and neonatal outcomes associated with preeclampsia among Omani women: A restrospective unmatched case control study.Women's health (London, England)Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preeclampsia is associated with an increased risk of adverse maternal and perinatal outcomes. This study aimed to assess preeclampsia prevalence in a Malaysian referral maternity hospital and the association between preeclampsia and maternal characteristics and outcomes. Methods: A cross-sectional study was conducted between January 2010 and December 2020 using secondary data from a single tertiary healthcare center in Greater Kuala Lumpur, Malaysia. A total of 40,212 deliveries were included for analysis to investigate the association between conditions (maternal characteristics and adverse birth outcomes) and preeclampsia. Multivariable logistic regression was conducted to assess the association between multiple independent variables and the outcome variable (preeclampsia). Results: The reported prevalence of preeclampsia was 1.6%. Pregnant women with preeclampsia had a higher risk of preterm delivery (67.7%), instrumental and cesarean delivery (74.7%), neonatal low birth weight (48.5%), neonatal 5-min Apgar score <7 (18.1%), and neonatal intensive care unit (NICU) admission (19.8%). There were significantly higher odds of developing preeclampsia among nullipara [adjusted odd ratio (adjOR) 1.792, 95% CI: 1.518-2.115], women with a previous history of preeclampsia (adjOR 5.345, 95% CI: 2.670-10.698) and women with multiple pregnancies (adjOR 1.658, 95% CI: 1.071-2.566). However, there is a significant association between maternal characteristic variables. There was a significant association when a combination of variables for risk assessment: the presence of anemia and gestational hypertension effect on preeclampsia (OR 26.344, 95% CI: 9.775-70.993, Conclusions: Nulliparity, previous history of preeclampsia, and multiple pregnancies were associated with an increased risk of preeclampsia. The presence of different underlying conditions, such as chronic hypertension, anemia, and extremes of maternal age played an important role in increasing preeclampsia risk in the considered study. Larger samples are needed to validate such findings.
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