ArticleCerebral circulation - cognition and behavior2022
Perforating artery flow velocity and pulsatility in patients with carotid occlusive disease. A 7 tesla MRI study.
Article in Cerebral circulation - cognition and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A novel early imaging biomarker for glymphatic function: Cerebral cortical arterial pulsatility index from 2-Minute phase-contrast MRI.The journal of prevention of Alzheimer's disease · 2025Article
- The Relation between Vascular Risk Factors and Flow in Cerebral Perforating Arteries: A 7 Tesla MRI Study.Cerebrovascular diseases (Basel, Switzerland) · 2025Article
- Changes in arterial flow velocity and pulsatility following endarterectomy for symptomatic high degree carotid artery stenosis: insights from the Carotis7T Study.Cerebral circulation - cognition and behavior · 2025Article
- Assessment of arterial pulsatility of cerebral perforating arteries using 7T high-resolution dual-VENC phase-contrast MRI.Magnetic resonance in medicine · 2024Article
- Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment.Acta neuropathologica communications · 2023Article
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Authors and funding
10 authors.
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Abstract
Patients with carotid occlusive disease express altered hemodynamics in the post-occlusive vasculature and lesions commonly attributed to cerebral small vessel disease (SVD). We addressed the question if cerebral perforating artery flow measures, using a novel 7T MRI technique, are altered and related to SVD lesion burden in patients with carotid occlusive disease. 21 patients were included with a uni- (18) or bilateral (3) carotid occlusion (64±7 years) and 19 controls (65±10 years). Mean flow velocity and pulsatility in the perforating arteries in the semi-oval center (CSO) and basal ganglia (BG), measured with a 2D phase contrast 7T MRI sequence, were compared between patients and controls, and between hemispheres in patients with unilateral carotid occlusive disease. In patients, relations were assessed between perforating artery flow measures and SVD burden score and white matter hyperintensity (WMH) volume. CSO perforating artery flow velocity was lower in patients than controls, albeit non-significant (mean difference [95% confidence interval] 0.08 cm/s [0.00-0.16];
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