Evidence map›Paper›PMID 36324393›Full record

ArticleCerebral circulation - cognition and behavior2022

Pulsatile tympanic membrane displacement is associated with cognitive score in healthy subjects.

Anthony A Birch, Wahbi K El-Bouri, Robert J Marchbanks, Laura A Moore, Cherith M Campbell-Bell, Christopher M Kipps, Diederik O Bulters

Abstract read
In one paragraph

Article in Cerebral circulation - cognition and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anthony A BirchNeurological Physics Group, Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Wahbi K El-BouriNeurological Physics Group, Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Robert J MarchbanksNeurological Physics Group, Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Laura A MooreNeurological Physics Group, Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Cherith M Campbell-BellNeurological Physics Group, Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Christopher M KippsUniversity of Southampton, Faculty of Medicine, Southampton, SO17 1BJ, UK.
Diederik O BultersUniversity of Southampton, Faculty of Medicine, Southampton, SO17 1BJ, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

To test the hypothesis that pulsing of intracranial pressure has an association with cognition, we measured cognitive score and pulsing of the tympanic membrane in 290 healthy subjects. This hypothesis was formed on the assumptions that large intracranial pressure pulses impair cognitive performance and tympanic membrane pulses reflect intracranial pressure pulses. 290 healthy subjects, aged 20-80 years, completed the Montreal Cognitive Assessment Test. Spontaneous tympanic membrane displacement during a heart cycle was measured from both ears in the sitting and supine position. We applied multiple linear regression, correcting for age, heart rate, and height, to test for an association between cognitive score and spontaneous tympanic membrane displacement. Significance was set at

Indexed as

Cognitive assessmentIntracranial pressureMOCAPulsatilityTympanic membrane displacement

Identifiers

PMID36324393
PMCPMC9616339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.