Evidence map›Paper›PMID 36324285›Full record

ArticlePhysiological reports2022

Impact of the downstream myocardial mass on values of coronary microvascular resistance.

Tadashi Murai, Hiroyuki Hikita, Tim P van de Hoef, Yoshinori Kanno, Fumiyuki Abe, Keiichi Hishikari, Munehiro Iiya, Naruhiko Ito, Hiroshi Yoshikawa, Hirotaka Yano and 5 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Tadashi MuraiCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.ORCID https://orcid.org/0000-0002-6766-4296
Hiroyuki HikitaCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Tim P van de HoefHeart Center, Amsterdam UMC, Amsterdam, The Netherlands.
Yoshinori KannoDepartment of Cardiovascular Medicine, Tokyo Medical Dental University Hospital, Tokyo, Japan.
Fumiyuki AbeDepartment of Cardiology, Ome Municipal General Hospital, Tokyo, Japan.
Keiichi HishikariCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Munehiro IiyaCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Naruhiko ItoCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Hiroshi YoshikawaCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Hirotaka YanoCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Wataru TsunoCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Atsushi TakahashiCardiovascular Center, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Taishi YonetsuDepartment of Cardiovascular Medicine, Tokyo Medical Dental University Hospital, Tokyo, Japan.
Tsunekazu KakutaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Tetsuo SasanoDepartment of Cardiovascular Medicine, Tokyo Medical Dental University Hospital, Tokyo, Japan.
Yokosuka Kyosai Hospital · JPTokyo Medical and Dental University Hospital · JPAmsterdam Neuroscience · NLOme Municipal General Hospital · JPTsuchiura Kyodo General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The assessment of hyperemic microvascular resistance (HMR) may be dependent on the assessment location in the coronary artery and the amount of partial myocardial mass (PMM) distal to the assessment locations. The aim of this study was to investigate the differences in HMR values between the distal and proximal sites in the same coronary arteries as well as the relationship between HMR and PMM. Twenty-nine vessels from 26 patients who had undergone intracoronary physiological assessments including Doppler flow velocity at the distal third part and the proximal third part in the same vessels were assessed. The mean values of HMR and PMM at the distal sites were 2.08 ± 0.75 mmHg/cm/sec and 22.2 ± 10.4 g, respectively. At the proximal sites, the values of HMR and PMM were 1.19 ± 0.33 mmHg/cm/sec and 59.9 ± 18.3 g, respectively. All HMR values at the distal sites were significantly higher than those at the proximal sites (p < 0.001). Smaller PMM at the distal sites was significantly associated with higher HMR (r = -0.544, p = 0.002) and was the strongest factor affecting the HMR values (p = 0.009), while this relationship was not observed at the proximal sites (r = -0.262, p = 0.17). The impact of PMM on HMR was diminished at assessment locations where PMM was greater than 35 g. In conclusion, a small amount of downstream myocardial mass could be related to high HMR values. The assessment location around the proximal coronary artery with over 35 g of myocardium would be appropriate to assess HMR because it minimizes the influence of the assessment location.

Indexed as

Coronary CirculationHyperemiaBlood Flow VelocityCardiac CatheterizationCoronary VesselsHumansMicrocirculationVascular Resistancecoronary blood flowcoronary microvascular resistancecoronary physiologymyocardial mass

Identifiers

PMID36324285
PMCPMC9630753
OpenAlexW4308181371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.