ArticleThe Journal of international medical research2022
The ultrastructural and morphological characteristics of the anterior cruciate ligament of the pig: a study using 7.0-Tesla diffusion tensor imaging.
Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- The effect of microstructural variations in tendon and ligament on diffusion tensor MRI.bioRxiv : the preprint server for biology · 2026Article
- Magnetic resonance imaging of cruciate ligament disorders: current updates.EFORT open reviews · 2025Review
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
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Abstract
objectiveDiffusion tensor imaging research on the anterior cruciate ligament (ACL) is limited, and no study has revealed the ACL fibrous microstructure by 7.0-Tesla magnetic resonance imaging. Therefore, we used magnetic resonance imaging to assess the ACL.
methodsEight porcine ACLs were investigated by diffusion tensor imaging. Imaging was performed with a 7.0-Tesla scanner using a diffusion-weighted two-dimensional spin-echo echo-planar imaging pulse sequence optimised for muscle. The diffusion tensor eigenparameters, fractional anisotropy (FA), and apparent diffusion coefficient (ADC) were used for bones and muscles. Three-dimensional projection maps of the principal eigenvectors were plotted to visualise the microstructure.
resultsThe mean FA and ADC for the ACL were 0.27 ± 0.079 and 0.0012 ± 0.0005, respectively. There were no significant differences between the values in the proximal and distal portions . However, the ADC was smaller in the centre than on the sides (0.0015 ± 0.0007), and the mean FA was larger in the centre than on the sides (0.42 ± 0.23). The ACL fibres were parallel on the proximal and distal sides but interweaved in the centre.
conclusionsThese findings may be beneficial for artificial ligaments.
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