Evidence map›Paper›PMID 36324099›Full record

ArticleBMC surgery2022

Obesity paradox among patients undergoing total knee arthroplasty: a retrospective cohort study.

Lulu Ma, Xuerong Yu, Xisheng Weng, Jin Lin, Wenwei Qian, Yuguang Huang

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Analysis of the Resolution Rate of Complications in Obese Joint Replacement Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lulu MaDepartment of Anesthesiology, Peking Union Medical College Hospital, 100730, Beijing, China.
Xuerong YuDepartment of Anesthesiology, Peking Union Medical College Hospital, 100730, Beijing, China. yxr313@aliyun.com.
Xisheng WengDepartment of Orthopedics, Peking Union Medical College Hospital, 100730, Beijing, China.
Jin LinDepartment of Orthopedics, Peking Union Medical College Hospital, 100730, Beijing, China.
Wenwei QianDepartment of Orthopedics, Peking Union Medical College Hospital, 100730, Beijing, China.
Yuguang HuangDepartment of Anesthesiology, Peking Union Medical College Hospital, 100730, Beijing, China.
Peking Union Medical College Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity has been recognized as the risk factor for postoperative complication for surgical patients. However, recent studies have showed protective effect of obesity in surgical and non-surgical patients. Our study is to examine the association of body mass index(BMI) with early postoperative complications in patients undergoing total knee arthroplasty. MATERIALS AND

methodsAll patients who had primary total knee arthroplasty between January 2014 and December 2019 were included. Medical records were retrospectively reviewed and BMI was categorized as underweight(BMI < 18.5), normal weight(18.5 < BMI < 24.9), overweight I(25 < BMI < 27.4), overweight II(27.5 < BMI < 29.9), obese I(30 < BMI < 34.9) and obese II(BMI ≥ 35). The association between BMI and occurrence of early postoperative complications was examined and logistic regression was used to calculate relationship between BMI and early postoperative complications.

resultsA total of 2969 patients were included in our analysis. The overall complication rate in patients undergoing total knee arthroplasty was 14.8%, with the highest complication being 22.2% in the underweight group, the second highest in the normal weight group(17.5%), the lowest in the overweight I(13.8%) and obese I(12.0%) group and then higher again in obese II group(16.7%). In multivariable analyses, overweight I (OR 0.737, 95% CI 0.559-0.972, P = 0.031) and obese I (OR 0.631, 95% CI 0.449-0.885, P = 0.008) were associated with lower risk of early postoperative complications after total knee arthroplasty.

conclusionIn this retrospective study, overweight and obese patients had a lower risk of early postoperative complications after total knee arthroplasty. Further studies are necessary to confirm and investigate the mechanism of obesity paradox in this surgical population.

trial registrationThis study had been registrated in www.chictr.org.cn on 25/10/2021 and the registration ID was ChiCTR2100052408.

Indexed as

Arthroplasty, Replacement, KneeObesity, MorbidBody Mass IndexHumansObesityOverweightPostoperative ComplicationsRetrospective StudiesRisk FactorsThinnessObesity paradoxPostoperative complicationsTotal knee arthroplasty

Identifiers

PMID36324099
PMCPMC9632147
OpenAlexW4307922296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.