Evidence map›Paper›PMID 36324081›Full record

Trial reportBMC anesthesiology2022

The effect of varying inhaled oxygen concentrations of high-flow nasal cannula oxygen therapy during gastroscopy with propofol sedation in elderly patients: a randomized controlled study.

Wenwen Zhang, Hailing Yin, Yajie Xu, Zhaojing Fang, Wanling Wang, Chen Zhang, Hongwei Shi, Xiaoliang Wang

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. High-flow nasal oxygen in anesthesiology practice.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenwen ZhangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hailing YinDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yajie XuDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Zhaojing FangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Wanling WangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Chen ZhangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hongwei ShiDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xiaoliang WangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. wxl145381@njmu.edu.cn.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite evidence that high-flow nasal cannula oxygen therapy (HFNC) promotes oxygenation, its application in sedated gastroscopy in elderly patients has received little attention. This study investigated the effect of different inhaled oxygen concentrations (FiO

methodsIn a prospective randomized single-blinded study, 369 outpatients undergoing regular gastroscopy with propofol sedation delivered by an anesthesiologist were randomly divided into three groups (n = 123): nasal cannula oxygen group (Group C), 100% FiO

resultsThe incidence of hypoxia, paradoxical response, choking, jaw lift, and mask ventilation was lower in both Group H100 and Group H50 than in Group C (P < 0.05). Compared with Group H100, Group H50 showed no significant differences in the incidence of hypoxia, jaw lift and mask ventilation, paradoxical response, or choking (P > 0.05). No patients were mechanically ventilated with endotracheal intubation or found to have complications from HFNC.

conclusionHFNC prevented hypoxia during gastroscopy with propofol in elderly patients, and there was no significant difference in the incidence of hypoxia when FiO

trial registrationThis single-blind, prospective, randomized controlled trial was approved by the Ethics Committee of Nanjing First Hospital (KY20201102-04) and registered in the China Clinical Trial Center (20/10/2021, ChiCTR2100052144) before patients enrollment. All patients signed an informed consent form.

Indexed as

Airway ObstructionPropofolRespiratory InsufficiencyAgedCannulaGastroscopyHumansHypoxiaOxygenOxygen Inhalation TherapyProspective StudiesSingle-Blind MethodOxygenPropofolElderly patientsGastroscopyHigh-flow nasal cannulaHypoxiaInhaled oxygen concentrationsSedation

Identifiers

PMID36324081
PMCPMC9628057
OpenAlexW4308139145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.