Evidence map›Paper›PMID 36324079›Full record

ArticleBasic and clinical andrology2022

An evaluation of the population characteristics, semen quality, and utilization status of autologous sperm cryopreservation and fertility preservation in for 662 patients: a 6-year monocentric retrospective study.

Wenhao Tang, Chenyao Deng, Jiangman Gao, Senlin Tian, Nan Wei, Bin Li, Jianfei Song, Liang Zhang, Han Wu, Hui Jiang

Open access · goldAbstract read
In one paragraph

Article in Basic and clinical andrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wenhao Tang *Department of Urology, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Chenyao Deng *Department of Urology, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Jiangman GaoDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Senlin TianDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Nan WeiDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Bin LiDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Jianfei SongDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Liang ZhangDepartment of Reproductive Medicine Center, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China.
Han WuDepartment of Urology, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China. 1293107264@qq.com.
Hui JiangDepartment of Urology, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China. jianghui@bjmu.edu.cn.
Peking University · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSperm cryopreservation is an effective method of fertility preservation for disease-related and social sperm freezing. In total, 662 subjects (range: 15-65 years-of-age; mean: 33.49 ± 8.79 years-of-age) were included in this study to investigate the population characteristics, semen quality, and usage of autologous sperm preservation patients in Beijing. Of these, 351 were cancer patients (53.02%, 31.14 ± 7.32 years-of-age) and 311 were non-cancer patients (46.98%, 36.14 ± 9.54 years-of-age).

resultsWe found that the number of preservation cases increased steadily from 2015 to 2019; 89.73% of these had a bachelor's degree or above; 54.83%, 41.54%, and 3.63% were single, married, and divorced, respectively. The cases of cancers and oligozoospermia accounted for 71.30% of all patients; therefore, most patients required fertility preservation due to disease. The cancer group had a significantly lower sperm concentration, rate of progressive sperm after the frozen-thawed test, total progressive motility sperm count after the frozen-thawed test, and recovery rate of progressive motile sperm (RRPM) than the non-cancer group (all P < 0.05). Sperm count-related parameters were significantly affected by testicular cancer, while sperm motility-related parameters and RRPM were significantly affected by leukemia. The utilization rate of preserved sperm was 6.34% after 6 to 78 months of follow-up. In terms of fresh or frozen embryo transfer, the clinical pregnancy rate was 56.76% or 50.00%, and the live birth rate was 24.32% or 21.43%, respectively.

conclusionThe need for autologous sperm preservation was dominated by patients with diseases, followed by the need for social sperm freezing. Tumors had a major negative impact on semen quality, and the usage rates of stored semen were at lower level compared to the number of sperm cryopreservation. Medical staff and patients should pay attention to both cognition-action consistency and cost-effectiveness in fertility preservation.

Indexed as

CancerFertility preservationMaleOnco-fertilitySemen cryopreservationSperm banking

Identifiers

PMID36324079
PMCPMC9629882
OpenAlexW4292510264

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.