Evidence map›Paper›PMID 36323862›Full record

ArticleNeuroradiology2023

Accuracy of automated intracerebral hemorrhage volume measurement on non-contrast computed tomography: a Swedish Stroke Register cohort study.

Amir Hillal, Gabriella Sultani, Birgitta Ramgren, Bo Norrving, Johan Wassélius, Teresa Ullberg

Abstract read
In one paragraph

Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amir HillalMedical Imaging and Physiology, Skåne University Hospital, 221 85, Lund, Sweden.
Gabriella SultaniDepartment of Clinical Sciences Lund, Lund University, 221 85, Lund, Sweden.
Birgitta RamgrenMedical Imaging and Physiology, Skåne University Hospital, 221 85, Lund, Sweden.
Bo NorrvingDepartment of Clinical Sciences Lund, Lund University, 221 85, Lund, Sweden.
Johan WasséliusMedical Imaging and Physiology, Skåne University Hospital, 221 85, Lund, Sweden. johan.wasselius@gmail.com.ORCID http://orcid.org/0000-0003-1896-381X
Teresa UllbergDepartment of Clinical Sciences Lund, Lund University, 221 85, Lund, Sweden.

Funding

AIDA 2024Crafoordska Stiftelsen 20200548Region of Skåne 47455Skånes universitetssjukhus 96437Skånes universitetssjukhus 96438The Swedish Government YF-ALF 43435VINNOVA 2020-04841
6 · The paper itself

Abstract

purposeHematoma volume is the strongest predictor of patient outcome after intracerebral hemorrhage (ICH). The aim of this study was to validate novel fully automated software for quantification of ICH volume on non-contrast computed tomography (CT).

methodsThe population was defined from the Swedish Stroke Register (RS) and included all patients with an ICH diagnosis during 2016-2019 in Region Skåne. Hemorrhage volume on their initial head CT was measured using ABC/2 and manual segmentation (Sectra IDS7 volume measurement tool) and the automated volume quantification tool (qER-NCCT) by Qure.ai. The first 500 were examined by two independent readers.

resultsA total of 1649 ICH patients were included. The qER-NCCT had 97% sensitivity in identifying ICH. In total, there was excellent agreement between volumetric measurements of ICH volumes by qER-NCCT and manual segmentation by interclass correlation (ICC = 0.96), and good agreement (ICC = 0.86) between qER-NCCT and ABC/2 method. The qER-NCCT showed volume underestimation, mainly in large (> 30 ml) heterogenous hemorrhages. Interrater agreement by (ICC) was 0.996 (95% CI: 0.99-1.00) for manual segmentation.

conclusionOur study showed excellent agreement in volume quantification between the fully automated software qER-NCCT and manual segmentation of ICH on NCCT. The qER-NCCT would be an important additive tool by aiding in early diagnostics and prognostication for patients with ICH and in provide volumetry on a population-wide level. Further refinement of the software should address the underestimation of ICH volume seen in a portion of large, heterogenous, irregularly shaped ICHs.

Indexed as

Cerebral HemorrhageStrokeCohort StudiesHematomaHumansSwedenTomography, X-Ray ComputedAutomated image analysis softwareBrainIntracerebral hemorrhageNon-contrast computed tomography

Identifiers

PMID36323862
PMCPMC9905189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.