Evidence map›Paper›PMID 36323776›Full record

ArticleNature2022

Histone H2B.8 compacts flowering plant sperm through chromatin phase separation.

Toby Buttress, Shengbo He, Liang Wang, Shaoli Zhou, Gerhard Saalbach, Martin Vickers, Guohong Li, Pilong Li, Xiaoqi Feng

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
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  9. Intermediate evolutionary state of motile sperm and pollen tubes in the extant gymnospermProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  11. Review
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  17. Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025
    Review
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Toby Buttress *Cell and Developmental Biology Department, John Innes Centre, Norwich, UK.ORCID http://orcid.org/0000-0001-5643-3508
Shengbo He *Cell and Developmental Biology Department, John Innes Centre, Norwich, UK.ORCID http://orcid.org/0000-0003-3773-9995
Liang Wang *Beijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Shaoli Zhou *Cell and Developmental Biology Department, John Innes Centre, Norwich, UK.
Gerhard SaalbachCell and Developmental Biology Department, John Innes Centre, Norwich, UK.
Martin VickersCell and Developmental Biology Department, John Innes Centre, Norwich, UK.ORCID http://orcid.org/0000-0002-1543-4827
Guohong LiInstitute of Biophysics, Chinese Academy of Science, Beijing, China.ORCID http://orcid.org/0000-0003-2137-0783
Pilong LiBeijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. pilongli@mail.tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-1783-3100
Xiaoqi FengCell and Developmental Biology Department, John Innes Centre, Norwich, UK. xiaoqi.feng@jic.ac.uk.ORCID http://orcid.org/0000-0002-4008-1234
John Innes Centre · GBPeking University · CNInstitute of Biophysics · CN

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9773
6 · The paper itself

Abstract

Sperm chromatin is typically transformed by protamines into a compact and transcriptionally inactive state

Indexed as

ArabidopsisCell SizeChromatinHistonesPollenAT Rich SequenceCell NucleusCell Nucleus SizeGene Expression Regulation, PlantMutationPhase TransitionProtaminesTranscription, GeneticChromatinHistonesProtamines

Identifiers

PMID36323776
PMCPMC9668745
OpenAlexW4307931690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.