Evidence map›Paper›PMID 36323763›Full record

ArticleScientific reports2022

Positive effect of inaudible high-frequency components of sounds on glucose tolerance: a quasi-experimental crossover study.

Norie Kawai, Manabu Honda, Emi Nishina, Osamu Ueno, Ariko Fukushima, Rikka Ohmura, Nahiko Fujita, Tsutomu Oohashi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review of sensory systems deployed by epidermal keratinocytes.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Norie KawaiDepartment of Research and Development, Foundation for Advancement of International Science, Tsukuba, Japan. nkawai@fais.or.jp.
Manabu HondaDepartment of Information Medicine, National Center of Neurology and Psychiatry, Kodaira, Japan. honda@ncnp.go.jp.
Emi NishinaDepartment of Liberal Arts, The Open University of Japan, Chiba, Japan.
Osamu UenoDepartment of Information Medicine, National Center of Neurology and Psychiatry, Kodaira, Japan.
Ariko FukushimaCenter for Liberal Arts and Basic Education, Edogawa University, Nagareyama, Japan.
Rikka OhmuraDepartment of Liberal Arts, The Open University of Japan, Chiba, Japan.
Nahiko FujitaGraduate School of Arts and Sciences, University of Tokyo, Tokyo, Japan.
Tsutomu OohashiDepartment of Research and Development, Foundation for Advancement of International Science, Tsukuba, Japan.
Foundation for Advancement of International Science · JPNational Center of Neurology and Psychiatry · JPThe Open University of Japan · JPEdogawa University · JPTokyo University of the Arts · JP

Funding

JSPS KAKENHI 19H01093JSPS KAKENHI 20H04276JST Moonshot R&D JPMJMS2296
6 · The paper itself

Abstract

Although stress significantly impacts on various metabolic syndromes, including diabetes mellitus, most stress management techniques are based on psychological and subjective approaches. This study examined how the presence or absence of the inaudible high-frequency component (HFC) of sounds, which activates deep-brain structures, affects glucose tolerance in healthy participants using the oral glucose tolerance test (OGTT). Sounds containing HFC suppressed the increase in glucose levels measured by incremental area under the curve in the OGTT compared with the otherwise same sounds without HFC. The suppression effect of HFC was more prominent in the older age group and the group with high HbA1c. This suggests that sounds with HFC are more effective in improving glucose tolerance in individuals at a higher risk of glucose intolerance.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Glucose IntoleranceAgedBlood GlucoseCross-Over StudiesGlucoseGlucose Tolerance TestGlycated HemoglobinHumansBlood GlucoseGlucoseGlycated Hemoglobin

Identifiers

PMID36323763
PMCPMC9630438
OpenAlexW4307920226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.