Evidence map›Paper›PMID 36323748›Full record

ArticleScientific reports2022

Antibiotic properties of Satureja montana L. hydrolate in bacteria and fungus of clinical interest and its impact in non-target environmental microorganisms.

María Rosa Pino-Otín, Cristina Gan, Eva Terrado, María Angeles Sanz, Diego Ballestero, Elisa Langa

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. TiOMolecules (Basel, Switzerland) · 2025
    Article
  3. Effects ofInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Effect ofBiomolecules · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Use of Essential Oil Emulsions to ControlFoods (Basel, Switzerland) · 2023
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

María Rosa Pino-OtínUniversidad San Jorge, Campus Universitario Villanueva de Gállego Autovía A-23 Zaragoza-Huesca, Km. 510, Villanueva de Gállego, 50830, Zaragoza, Spain. rpino@usj.es.
Cristina GanUniversidad San Jorge, Campus Universitario Villanueva de Gállego Autovía A-23 Zaragoza-Huesca, Km. 510, Villanueva de Gállego, 50830, Zaragoza, Spain.
Eva TerradoUniversidad de Zaragoza, C. de Pedro Cerbuna, 12, 50009, Zaragoza, Spain.
María Angeles SanzCITA, Área de Laboratorios de Análisis y Asistencia Tecnológica, Avda. Montañana 930, 50059, Zaragoza, Spain.
Diego BallesteroUniversidad San Jorge, Campus Universitario Villanueva de Gállego Autovía A-23 Zaragoza-Huesca, Km. 510, Villanueva de Gállego, 50830, Zaragoza, Spain.
Elisa LangaUniversidad San Jorge, Campus Universitario Villanueva de Gállego Autovía A-23 Zaragoza-Huesca, Km. 510, Villanueva de Gállego, 50830, Zaragoza, Spain.
Universidad San Jorge · ESCentro de Investigación y Tecnología Agroalimentaria de Aragón · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to analyse the microbicidal and microbiostatic activity of S. montana hydrolate L., the water-soluble fraction of the hydro-distillation process used to obtain the essential oil, on 14 Gram-positive and Gram-negative bacteria and a fungus of clinical interest. To consider whether this hydrolate is a more environmentally friendly alternative to traditional antibiotics, its effect on non-target microorganisms in the aquatic and terrestrial environment was analysed using natural soil and river microorganism communities, characterized through 16S rRNA gene sequencing. Results showed that S. montana hydrolate was especially effective (25% v/v concentration) against Pasteurella aerogenes, Streptococcus agalactiae and Acinetobacter baumannii (priority 1, WHO). It was also a microbicide for a further 7 bacterial strains and the fungus Candida albicans (50% v/v concentration). The river and soil communities exposed to the hydrolate showed a decrease in their growth, as well as a decrease in their ability to metabolize polymers and carbohydrates (soil microorganisms) and polymers, carboxylic and ketone acids (river microorganisms). Hydrolates could be an alternative to conventional antibiotics, but their impact on the environment must be taken into account.

Indexed as

Anti-Infective AgentsSaturejaAnti-Bacterial AgentsBacteriaFungiGram-Negative BacteriaGram-Positive BacteriaMontanaPolymersRNA, Ribosomal, 16SSoilAnti-Bacterial AgentsAnti-Infective AgentsPolymersRNA, Ribosomal, 16SSoil

Identifiers

PMID36323748
PMCPMC9630514
OpenAlexW4307989693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.